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Oct4 ~ 注目ターゲットのおすすめ製品

ウサギ・モノクローナル 抗体

ターゲット名

交差種

適用・アプリケーション

文献

Abreview
数 評価

製品番号

Oct4 HuFlow Cyt, IHC-P, IP, WB91
ab109183
Oct4 Hu, MsChIP, ICC/IF, IHC-P, IP, WB511
ab181557
Oct4 Hu, MsFlow Cyt, ICC/IF, IHC-P, IP, WB 1
ab200834
Oct4 HuIHC-P ab194076
Oct4
Alexa Fluor® 488
HuICC/IF ab194074

抗体

ターゲット名

交差種

適用・アプリケーション

文献

Abreview
数 評価

製品番号

Oct4
Alexa Fluor® 488
Rb-P MsICC/IF ab197273
Oct4
Alexa Fluor® 647
Rb-P Ms, Shp, Hu, RMkICC/IF ab196585
Oct4Rb-PHu, Ms, RMk, ShpChIP, CHIPseq, Flow Cyt, ICC/IF, IHC-Fr, IHC-P, IP, WB22639 ab19857
Oct4Rb-P Ms, Rat, Hu, Pig, McqFlow Cyt, ICC/IF, IHC-Fr, IHC-P, IP, WB6711ab18976
Oct4Goat-PHu, Ms, RatFlow Cyt, ICC/IF, WB4310ab27985
Oct4Rb-PHu, MsFlow Cyt, ICC/IF, WB3 ab137427
Oct4Ms-MHu, Ms, RatICC/IF, IHC-P2 ab59545
Oct4Chk-P MsICC/IF, WB1 ab134218
抗体一覧

タンパク質・ペプチド

製品名

由来

適用・アプリケーション

製品番号

Oct4 protein fragment (Recombinant)HuDot, I-ELISA, SDS-PAGE, WBab95845
Oct4 full length protein(Recombinant)HuELISA, SDS-PAGE, WBab131955
Oct4 full length protein (Active )HuFuncS, SDS-PAGEab134876
Oct4 full length protein(Active )HuFuncS, SDS-PAGEab169842
Oct4 peptideHuBLab20650
タンパク質・ペプチド一覧

キット

製品名

交差種

容量

製品番号

Oct4 Transcription Factor Assay Kit (Colorimetric) Hu, Ms, Rat5x96tests
1x96tests
ab207224
Human Embryonic Stem Cell Marker Panel (Oct4, Nanog, Tra-1-60, SOX2 and SSEA4)1uab109884
Mouse Embryonic Stem Cell Marker Panel (Oct4, Nanog, SOX2, SSEA1)1uab107156

Oct4について

Function
機能
Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). Forms a trimeric complex with SOX2 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency.
Tissue specificity
組織特異性
Expressed in developing brain. Highest levels found in specific cell layers of the cortex, the olfactory bulb, the hippocampus and the cerebellum. Low levels of expression in adult tissues.
Sequence similarities
配列類似性
  • Belongs to the POU transcription factor family.
  • Class-5 subfamily.
  • Contains 1 homeobox DNA-binding domain.
  • Contains 1 POU-specific domain.
Post-translational modifications
翻訳後修飾
Sumoylation enhances the protein stability, DNA binding and transactivation activity. Sumoylation is required for enhanced YES1 expression. Ubiquitinated; undergoes 'Lys-63'-linked polyubiquitination by WWP2 leading to proteasomal degradation.
Cellular localization
細胞内局在性
Nucleus. Expressed in a diffuse and slightly punctuate pattern.

関連リンク


注目ターゲット

Alexa Fluor® is a registered trademark of Life Technologies. Alexa Fluor® dye conjugates contain(s) technology licensed to Abcam by Life Technologies.


ウサギ・モノクローナル 抗体

ターゲット名

交差種

適用・アプリケーション

文献

Abreview
数 評価

製品番号

Oct4 HuFlow Cyt, IHC-P, IP, WB91
ab109183
Oct4 Hu, MsChIP, ICC/IF, IHC-P, IP, WB511
ab181557
Oct4 Hu, MsFlow Cyt, ICC/IF, IHC-P, IP, WB 1
ab200834
Oct4 HuIHC-P ab194076
Oct4
Alexa Fluor® 488
HuICC/IF ab194074

抗体

ターゲット名

交差種

適用・アプリケーション

文献

Abreview
数 評価

製品番号

Oct4
Alexa Fluor® 488
Rb-P MsICC/IF ab197273
Oct4
Alexa Fluor® 647
Rb-P Ms, Shp, Hu, RMkICC/IF ab196585
Oct4Rb-PHu, Ms, RMk, ShpChIP, CHIPseq, Flow Cyt, ICC/IF, IHC-Fr, IHC-P, IP, WB22639 ab19857
Oct4Rb-P Ms, Rat, Hu, Pig, McqFlow Cyt, ICC/IF, IHC-Fr, IHC-P, IP, WB6711ab18976
Oct4Goat-PHu, Ms, RatFlow Cyt, ICC/IF, WB4310ab27985
Oct4Rb-PHu, MsFlow Cyt, ICC/IF, WB3 ab137427
Oct4Ms-MHu, Ms, RatICC/IF, IHC-P2 ab59545
Oct4Chk-P MsICC/IF, WB1 ab134218
抗体一覧

タンパク質・ペプチド

製品名

由来

適用・アプリケーション

製品番号

Oct4 protein fragment (Recombinant)HuDot, I-ELISA, SDS-PAGE, WBab95845
Oct4 full length protein(Recombinant)HuELISA, SDS-PAGE, WBab131955
Oct4 full length protein (Active )HuFuncS, SDS-PAGEab134876
Oct4 full length protein(Active )HuFuncS, SDS-PAGEab169842
Oct4 peptideHuBLab20650
タンパク質・ペプチド一覧

キット

製品名

交差種

容量

製品番号

Oct4 Transcription Factor Assay Kit (Colorimetric) Hu, Ms, Rat5x96tests
1x96tests
ab207224
Human Embryonic Stem Cell Marker Panel (Oct4, Nanog, Tra-1-60, SOX2 and SSEA4)1uab109884
Mouse Embryonic Stem Cell Marker Panel (Oct4, Nanog, SOX2, SSEA1)1uab107156

Oct4について

Function
機能
Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). Forms a trimeric complex with SOX2 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency.
Tissue specificity
組織特異性
Expressed in developing brain. Highest levels found in specific cell layers of the cortex, the olfactory bulb, the hippocampus and the cerebellum. Low levels of expression in adult tissues.
Sequence similarities
配列類似性
  • Belongs to the POU transcription factor family.
  • Class-5 subfamily.
  • Contains 1 homeobox DNA-binding domain.
  • Contains 1 POU-specific domain.
Post-translational modifications
翻訳後修飾
Sumoylation enhances the protein stability, DNA binding and transactivation activity. Sumoylation is required for enhanced YES1 expression. Ubiquitinated; undergoes 'Lys-63'-linked polyubiquitination by WWP2 leading to proteasomal degradation.
Cellular localization
細胞内局在性
Nucleus. Expressed in a diffuse and slightly punctuate pattern.

関連リンク


注目ターゲット

Alexa Fluor® is a registered trademark of Life Technologies. Alexa Fluor® dye conjugates contain(s) technology licensed to Abcam by Life Technologies.


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