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Bax ~ 注目ターゲットのおすすめ製品


ウサギ・モノクローナル 抗体

ターゲット名

交差種

適用・アプリケーション

文献

Abreview
数 評価

製品番号

Bax
Hu, Ms, RatIHC-P, IP, sELISA, WB11713 ab32503
Bax HuFlow Cyt, IHC-P ab81083
Bax
Hu, Ms, RatIP, WB4 1ab182733
Bax
BSA and Azide free
Ms, Rat, Hu, ChHm ab216985
Bax HRP ab205822

抗体

ターゲット名

交差種

適用・アプリケーション

文献

Abreview
数 評価

製品番号

BaxRb-P
HuWB ab104156
BaxMs-MHuFlow Cyt, ICC/IF, IHC-P, sELISA, WB9 ab77566
Bax (pT167)Rb-P Ms, Rat, HuICC/IF ab192819
Bax
BSA and Azide free
Hu, Mk IHC-P, WB, ICC/IF, Flow Cyt ab212790
抗体一覧

タンパク質・ペプチド

製品名

由来

適用・アプリケーション

製品番号

Bax full length protein (Recombinant)(Tagged)HuWB, SDS-PAGEab85157
Bax inhibitor 1 full length protein (Recombinant)HuELISA, SDS-PAGE, WBab152735
Bax protein fragment (Recombinant)HuHPLC, SDS-PAGEab173026
Bax protein fragment (Recombinant)MsWB,FunSab59854
タンパク質・ペプチド一覧

キット

製品名

交差種

容量

製品番号

Bax ELISA Kit Hu1x96testsab199080
Bax ELISA Kit Ms1x96testsab233624
Bax ELISA KitDog, Hu1x96testsab133048
Human Apoptosis Antibody Array - Membrane (43 Targets)Hu1x2memb
1x4memb
1x8memb
ab134001

Bax について

Function
(機能)
Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.
Tissue specificity
(組織特異性)
Expressed in a wide variety of tissues. Isoform Psi is found in glial tumors. Isoform Alpha is expressed in spleen, breast, ovary, testis, colon and brain, and at low levels in skin and lung. Isoform Sigma is expressed in spleen, breast, ovary, testis, lung, colon, brain and at low levels in skin. Isoform Alpha and isoform Sigma are expressed in pro-myelocytic leukemia, histiocytic lymphoma, Burkitt's lymphoma, T-cell lymphoma, lymphoblastic leukemia, breast adenocarcinoma, ovary adenocarcinoma, prostate carcinoma, prostate adenocarcinoma, lung carcinoma, epidermoid carcinoma, small cell lung carcinoma and colon adenocarcinoma cell lines.
Sequence similarities
(配列類似性)
Belongs to the Bcl-2 family.
Domain
(領域)
Intact BH3 motif is required by BIK, BID, BAK, BAD and BAX for their pro-apoptotic activity and for their interaction with anti-apoptotic members of the Bcl-2 family.
Cellular localization
(細胞局在性)
Cytoplasm and Mitochondrion membrane.
Alternative names
(別名)
apoptosis regulator BAX antibody, Apoptosis regulator BAX cytoplasmic isoform beta antibody, Apoptosis regulator BAX membrane isoform alpha antibody, BAX antibody, Bax isoform psi antibody, BAX protein cytoplasmic isoform delta antibody, Bax protein cytoplasmic isoform delta. antibody ,Bax protein cytoplasmic isoform gamma antibody, Bax zeta antibody, Bax-protein antibody, BAX_HUMAN antibody, BAXA antibody, Bcl-2-like protein 4 antibody, BCL2 associated X protein antibody, BCL2 associated X protein omega antibody, BCL2 associated X protein transcript variant delta2 antibody, Bcl2-L-4 antibody, BCL2L4 antibody, membrane isoform alpha antibod

関連リンク


Cancer
ポータル

注目ターゲット

Apoptosis アッセイ・キット


ウサギ・モノクローナル 抗体

ターゲット名

交差種

適用・アプリケーション

文献

Abreview
数 評価

製品番号

Bax
Hu, Ms, RatIHC-P, IP, sELISA, WB11713 ab32503
Bax HuFlow Cyt, IHC-P ab81083
Bax
Hu, Ms, RatIP, WB4 1ab182733
Bax
BSA and Azide free
Ms, Rat, Hu, ChHm ab216985
Bax HRP ab205822

抗体

ターゲット名

交差種

適用・アプリケーション

文献

Abreview
数 評価

製品番号

BaxRb-P
HuWB ab104156
BaxMs-MHuFlow Cyt, ICC/IF, IHC-P, sELISA, WB9 ab77566
Bax (pT167)Rb-P Ms, Rat, HuICC/IF ab192819
Bax
BSA and Azide free
Hu, Mk IHC-P, WB, ICC/IF, Flow Cyt ab212790
抗体一覧

タンパク質・ペプチド

製品名

由来

適用・アプリケーション

製品番号

Bax full length protein (Recombinant)(Tagged)HuWB, SDS-PAGEab85157
Bax inhibitor 1 full length protein (Recombinant)HuELISA, SDS-PAGE, WBab152735
Bax protein fragment (Recombinant)HuHPLC, SDS-PAGEab173026
Bax protein fragment (Recombinant)MsWB,FunSab59854
タンパク質・ペプチド一覧

キット

製品名

交差種

容量

製品番号

Bax ELISA Kit Hu1x96testsab199080
Bax ELISA Kit Ms1x96testsab233624
Bax ELISA KitDog, Hu1x96testsab133048
Human Apoptosis Antibody Array - Membrane (43 Targets)Hu1x2memb
1x4memb
1x8memb
ab134001

Bax について

Function
(機能)
Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.
Tissue specificity
(組織特異性)
Expressed in a wide variety of tissues. Isoform Psi is found in glial tumors. Isoform Alpha is expressed in spleen, breast, ovary, testis, colon and brain, and at low levels in skin and lung. Isoform Sigma is expressed in spleen, breast, ovary, testis, lung, colon, brain and at low levels in skin. Isoform Alpha and isoform Sigma are expressed in pro-myelocytic leukemia, histiocytic lymphoma, Burkitt's lymphoma, T-cell lymphoma, lymphoblastic leukemia, breast adenocarcinoma, ovary adenocarcinoma, prostate carcinoma, prostate adenocarcinoma, lung carcinoma, epidermoid carcinoma, small cell lung carcinoma and colon adenocarcinoma cell lines.
Sequence similarities
(配列類似性)
Belongs to the Bcl-2 family.
Domain
(領域)
Intact BH3 motif is required by BIK, BID, BAK, BAD and BAX for their pro-apoptotic activity and for their interaction with anti-apoptotic members of the Bcl-2 family.
Cellular localization
(細胞局在性)
Cytoplasm and Mitochondrion membrane.
Alternative names
(別名)
apoptosis regulator BAX antibody, Apoptosis regulator BAX cytoplasmic isoform beta antibody, Apoptosis regulator BAX membrane isoform alpha antibody, BAX antibody, Bax isoform psi antibody, BAX protein cytoplasmic isoform delta antibody, Bax protein cytoplasmic isoform delta. antibody ,Bax protein cytoplasmic isoform gamma antibody, Bax zeta antibody, Bax-protein antibody, BAX_HUMAN antibody, BAXA antibody, Bcl-2-like protein 4 antibody, BCL2 associated X protein antibody, BCL2 associated X protein omega antibody, BCL2 associated X protein transcript variant delta2 antibody, Bcl2-L-4 antibody, BCL2L4 antibody, membrane isoform alpha antibod

関連リンク


Cancer
ポータル

注目ターゲット

Apoptosis アッセイ・キット

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