Biotin-VAD-FMK, pan-caspase inhibitor (ab142032)
Key features and details
- Pan-caspase inhibitor
- CAS Number:
- Purity: > 95%
- Supplied in DMSO (10 mM)
- Form / State: Liquid
- Source: Synthetic
製品の概要
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製品名
Biotin-VAD-FMK, pan-caspase inhibitor -
製品の詳細
Pan-caspase inhibitor -
生理活性の詳細
Irreversible, pancaspase inhibitor. Inhibits TNFα-mediated apoptosis in vitro (IC50 = 0.7 μM). Immunosuppressive, inhibits T cell proliferation. Active in vivo and in vitro. Cell-permeable. -
精製度
> 95% -
構造式
製品の特性
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分子量
672.81 -
分子式
C30H49FN6O8S -
配列
VAD (Modifications: N-terminal biotinyl; C-terminal FMK; Asp-3 = Asp(OMe)) -
PubChem 登録番号
44135213 -
保存方法
Store at -20°C (desiccating conditions). -
溶解性
Supplied in DMSO (10 mM) -
使用に関する注意
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one week. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES 線形表記
CC(C)C(C(=O)NC(C)C(=O)NC(CC(=O)OC)C(=O)CF)NC(=O)CCCCCNC(=O)CCCCC1C2C(CS1)NC(=O)N2 -
由来
Synthetic
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研究分野
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (0)
ab142032 は論文での使用が確認できていません。