Biotin Anti-MHC class I 抗体 [AF6-88.5.5.3] (ab93528)
Key features and details
- Biotin Mouse monoclonal [AF6-88.5.5.3] to MHC class I
- Suitable for: Flow Cyt
- Reacts with: Mouse
- Conjugation: Biotin
- Isotype: IgG2a
製品の概要
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製品名
Biotin Anti-MHC class I antibody [AF6-88.5.5.3]
MHC class I 一次抗体 製品一覧 -
製品の詳細
Biotin Mouse monoclonal [AF6-88.5.5.3] to MHC class I -
由来種
Mouse -
標識
Biotin -
特異性
Reacts with the H-2Kb MHC class I alloantigen. Reactivity to other haplotypes (e.g. d, f, j, k, p, q, r, s, u, and v) has not been observed. -
アプリケーション
適用あり: Flow Cytmore details -
種交差性
交差種: Mouse -
免疫原
Tissue, cells or virus corresponding to Mouse MHC class I. C57BL Mouse splenocytes.
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ポジティブ・コントロール
- Splenocytes
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
バッファー
pH: 7.2
Preservative: 0.09% Sodium azide -
Concentration information loading...
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精製度
Affinity purified -
ポリ/モノ
モノクローナル -
クローン名
AF6-88.5.5.3 -
アイソタイプ
IgG2a -
研究分野
関連製品
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab93528の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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Flow Cyt |
特記事項 |
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Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
ターゲット情報
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関連性
MHC Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. MHC class I antigens are heterodimers consisting of one alpha chain (44kDa) with beta 2 microglobulin (11.5 kDa). The antigen is expressed by all somatic cells at varying levels. MHC Class I molecules are expressed on most nucleated cells where they present endogenously synthesized antigenic peptides to CD8+ T lymphocytes, which are usually cytotoxic T cells. Fibroblasts or neurons however only show a low level of antigen. -
細胞内局在
Cell Membrane; Type I membrane protein. -
別名
- A 28 antibody
- A 9 antibody
- Antigen presenting molecule antibody
see all
画像
データシートおよび資料
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Datasheet download
参考文献 (1)
ab93528 は 1 報の論文で使用されています。
- Neek M et al. An Antigen-Delivery Protein Nanoparticle Combined with Anti-PD-1 Checkpoint Inhibitor Has Curative Efficacy in an Aggressive Melanoma Model. Adv Ther (Weinh) 3:N/A (2020). PubMed: 34141865