Biotin Anti-CX3CR1 抗体 [2A9-1] (ab95620)
Key features and details
- Biotin Rat monoclonal [2A9-1] to CX3CR1
- Suitable for: Flow Cyt
- Reacts with: Human
- Conjugation: Biotin
- Isotype: IgG2b
製品の概要
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製品名
Biotin Anti-CX3CR1 antibody [2A9-1]
CX3CR1 一次抗体 製品一覧 -
製品の詳細
Biotin Rat monoclonal [2A9-1] to CX3CR1 -
由来種
Rat -
標識
Biotin -
アプリケーション
適用あり: Flow Cytmore details -
種交差性
交差種: Human -
免疫原
CX3CR1-EGFP fusion protein.
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ポジティブ・コントロール
- Normal Human peripheral blood cells.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
バッファー
pH: 7.2
Preservative: 0.09% Sodium azide -
Concentration information loading...
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精製度
Protein G purified -
ポリ/モノ
モノクローナル -
クローン名
2A9-1 -
アイソタイプ
IgG2b -
研究分野
関連製品
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab95620の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
---|---|---|
Flow Cyt |
Use 0.25µl for 105-8 cells.
Use a final volume of 100µl.
ab18542 - Rat monoclonal IgG2b, is suitable for use as an isotype control with this antibody.
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特記事項 |
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Flow Cyt
Use 0.25µl for 105-8 cells. Use a final volume of 100µl.
ab18542 - Rat monoclonal IgG2b, is suitable for use as an isotype control with this antibody.
|
ターゲット情報
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機能
Receptor for the CX3C chemokine fractalkine and mediates both its adhesive and migratory functions. Acts as coreceptor with CD4 for HIV-1 virus envelope protein (in vitro). Isoform 2 and isoform 3 seem to be more potent HIV-1 coreceptors than isoform 1. -
組織特異性
Expressed in lymphoid and neural tissues. -
配列類似性
Belongs to the G-protein coupled receptor 1 family. -
細胞内局在
Cell membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 1524 Human
- Omim: 601470 Human
- SwissProt: P49238 Human
- Unigene: 78913 Human
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別名
- Beta chemokine receptor-like 1 antibody
- C X3 C CKR 1 antibody
- C-X3-C CKR-1 antibody
see all
画像
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Staining of normal Human peripheral blood cells with 0.125µg/100µl rat IgG1 isotype control Biotin (left) or 0.125µg/100µl ab95620 (right), followed by Streptavidin PE.
Samples were subsequently stained intracellularly with an anti Human Perforin FITC. Cells were gated on CD16+CD56+ using anti-CD16 eFluor 450 and anti-CD56 APC antibodies.
データシートおよび資料
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Datasheet download
参考文献 (1)
ab95620 は 1 報の論文で使用されています。
- Sun C et al. ADAM17-regulated CX3CL1 expression produced by bone marrow endothelial cells promotes spinal metastasis from hepatocellular carcinoma. Int J Oncol 57:249-263 (2020). PubMed: 32319605