Biotin Anti-CD147 抗体 [MEM-M6/1] (ab21898)
![Flow Cytometry - Biotin Anti-CD147 antibody [MEM-M6/1] (ab21898)](https://www.abcam.co.jp/ps/products/21/ab21898/Images/ab21898-278856-anti-cd147-antibody-mem-m6-1-biotin-flow-cytometry.jpg "Flow Cytometry - Biotin Anti-CD147 antibody [MEM-M6/1] (ab21898)")
Key features and details
- Biotin Mouse monoclonal [MEM-M6/1] to CD147
- Suitable for: IP, WB, Flow Cyt
- Reacts with: Human
- Conjugation: Biotin
- Isotype: IgG1
Related conjugates and formulations
製品の概要
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製品名
Biotin Anti-CD147 antibody [MEM-M6/1]
CD147 一次抗体 製品一覧 -
製品の詳細
Biotin Mouse monoclonal [MEM-M6/1] to CD147 -
由来種
Mouse -
標識
Biotin -
アプリケーション
適用あり: IP, WB, Flow Cytmore details -
種交差性
交差種: Human -
免疫原
Recombinant full length protein (Human): Protein A CR purified soluble recombinant form of CD147, CD147Rg, which consists of the cDNA coding for the hinge region, CH2 and CH3 domain of human IgG1 (CD147Rg is secreted by transfectants as a dimmer).
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エピトープ
The epitope is localised in the N terminal Ig domain (D1) of CD147 antigen. -
ポジティブ･コントロール
- Flow cyt: human peripheral blood
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特記事項
ab21898 is a high-affinity antibody capable of binding to unstimulated peripheral blood T cells.
The purified antibody is conjugated with Biotin-LC-NHS under optimum conditions. The reagent is free of unconjugated biotin.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
バッファー
pH: 7.40
Preservative: 0.097% Sodium azide
Constituent: PBS -
Concentration information loading... -
精製度
Protein G purified -
特記事項（精製）
The purified antibody is conjugated with biotin-LC-NHS under optimum conditions. The reagent is free of unconjugated biotin. -
一次抗体 備考
ab21898 is a high-affinity antibody capable of binding to unstimulated peripheral blood T cells. -
ポリ/モノ
モノクローナル -
クローン名
MEM-M6/1 -
アイソタイプ
IgG1 -
研究分野
関連製品
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Alternative Versions
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab21898の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| IP |
Use at an assay dependent concentration.
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| WB |
Use at an assay dependent concentration.
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| Flow Cyt |
Use a concentration of 8 µg/ml.
ab18434 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.
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| 特記事項 |
|---|
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IP
Use at an assay dependent concentration. |
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WB
Use at an assay dependent concentration. |
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Flow Cyt
Use a concentration of 8 µg/ml. ab18434 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.
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ターゲット情報
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機能
Plays pivotal roles in spermatogenesis, embryo implantation, neural network formation and tumor progression. Stimulates adjacent fibroblasts to produce matrix metalloproteinases (MMPS). May target monocarboxylate transporters SLC16A1, SLC16A3 and SLC16A8 to plasma membranes of retinal pigment epithelium and neural retina. Seems to be a receptor for oligomannosidic glycans. In vitro, promotes outgrowth of astrocytic processes. -
組織特異性
Present only in vascular endothelium in non-neoplastic regions of the brain, whereas it is present in tumor cells but not in proliferating blood vessels in malignant gliomas. -
配列類似性
Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
Contains 1 Ig-like V-type (immunoglobulin-like) domain. -
翻訳後修飾
N-glycosylated. -
細胞内局在
Cell membrane. Melanosome. Colocalizes with SLC16A1 and SLC16A8 (By similarity). Identified by mass spectrometry in melanosome fractions from stage I to stage IV. - Information by UniProt
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参照データベース
- Entrez Gene: 682 Human
- Omim: 109480 Human
- SwissProt: P35613 Human
- Unigene: 501293 Human
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別名
- 5A11 antigen antibody
- 5F7 antibody
- BASI_HUMAN antibody
see all
画像
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Flow Cytometry - Biotin Anti-CD147 antibody [MEM-M6/1] (ab21898)Flow Cytometry analysis of Human peripheral blood cells labeling CD147 with Anti-CD147 antibody [MEM-M6/1] (Biotin) (ab21898).
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (0)
ab21898 は論文での使用が確認できていません。