Biotin Anti-CCR7 抗体 [4B12] (ab93519)
Key features and details
- Biotin Rat monoclonal [4B12] to CCR7
- Suitable for: Flow Cyt, ICC/IF
- Reacts with: Mouse
- Conjugation: Biotin
- Isotype: IgG2a
Related conjugates and formulations
製品の概要
-
製品名
Biotin Anti-CCR7 antibody [4B12]
CCR7 一次抗体 製品一覧 -
製品の詳細
Biotin Rat monoclonal [4B12] to CCR7 -
由来種
Rat -
標識
Biotin -
アプリケーション
適用あり: Flow Cyt, ICC/IFmore details -
種交差性
交差種: Mouse -
免疫原
Tissue, cells or virus corresponding to Mouse CCR7. Rat basophilic leukaemia (RBL)-2H3 cells transfectanted with Mouse CCR7.
-
ポジティブ・コントロール
- Splenocytes or thymocytes.
-
特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
-
製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
バッファー
pH: 7.20
Preservative: 0.09% Sodium azide
Constituents: 0.87% Sodium chloride, PBS -
Concentration information loading...
-
精製度
Protein G purified -
ポリ/モノ
モノクローナル -
クローン名
4B12 -
アイソタイプ
IgG2a -
軽鎖の種類
kappa -
研究分野
関連製品
-
Alternative Versions
-
Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab93519の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
---|---|---|
Flow Cyt |
Use at an assay dependent concentration.
|
|
ICC/IF |
Use at an assay dependent concentration.
|
特記事項 |
---|
Flow Cyt
Use at an assay dependent concentration. |
ICC/IF
Use at an assay dependent concentration. |
ターゲット情報
-
機能
Receptor for the MIP-3-beta chemokine. Probable mediator of EBV effects on B-lymphocytes or of normal lymphocyte functions. -
組織特異性
Expressed in various lymphoid tissues and activated B- and T-lymphocytes, strongly up-regulated in B-cells infected with Epstein-Barr virus and T-cells infected with herpesvirus 6 or 7. -
配列類似性
Belongs to the G-protein coupled receptor 1 family. -
細胞内局在
Cell membrane. - Information by UniProt
-
参照データベース
- Entrez Gene: 12775 Mouse
- SwissProt: P47774 Mouse
- Unigene: 2932 Mouse
-
別名
- BLR 2 antibody
- BLR2 antibody
- C C chemokine receptor type 7 antibody
see all
データシートおよび資料
-
Datasheet download
参考文献 (3)
ab93519 は 3 報の論文で使用されています。
- Waldner H et al. The autoimmune diabetes locus Idd9 regulates development of type 1 diabetes by affecting the homing of islet-specific T cells. J Immunol 176:5455-62 (2006). PubMed: 16622013
- Ohl L et al. CCR7 governs skin dendritic cell migration under inflammatory and steady-state conditions. Immunity 21:279-88 (2004). PubMed: 15308107
- Ritter U et al. Analysis of the CCR7 expression on murine bone marrow-derived and spleen dendritic cells. J Leukoc Biol 76:472-6 (2004). PubMed: 15197229