製品名beta-Amyloid Peptide (1-40) (human)
製品の詳細Amyloid beta (1-40) protein fragment. Implicated in Alzheimer's disease.
One of the two main alloforms of the amyloid beta peptide widely implicated in Alzheimer's disease. Displays neuroprotective properties preventing neuronal death.
保存方法Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
Soluble in DMSO to 1 mg/ml.
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one week. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
This product has been referenced in:
- Chen YR et al. Aß40(L17A/F19A) mutant diminishes the aggregation and neurotoxicity of Aß40. Biochem Biophys Res Commun 405:91-5 (2011). Read more (PubMed: 21216230) »
- Sgourakis NG et al. The Alzheimer's peptides Abeta40 and 42 adopt distinct conformations in water: a combined MD / NMR study. J Mol Biol 368:1448-57 (2007). Read more (PubMed: 17397862) »
- Zou K et al. Amyloid beta-protein (Abeta)1-40 protects neurons from damage induced by Abeta1-42 in culture and in rat brain. J Neurochem 87:609-19 (2003). Read more (PubMed: 14535944) »