Anti-BCS1L 抗体 (ab102808)
Key features and details
- Rabbit polyclonal to BCS1L
- Suitable for: WB
- Reacts with: Mouse, Human
- Isotype: IgG
製品の概要
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製品名
Anti-BCS1L antibody -
製品の詳細
Rabbit polyclonal to BCS1L -
由来種
Rabbit -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Mouse, Human -
免疫原
Recombinant full length protein, corresponding to amino acids 1-419 of Human BCS1L (NP_004319.1).
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ポジティブ･コントロール
- Mouse spleen tissue lysate; BCS1L transfected 293T cell line lysate
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
バッファー
pH: 7.4
Constituent: 2.68% PBS -
Concentration information loading... -
精製度
Protein A purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab102808の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB |
Use a concentration of 1 - 5 µg/ml. Predicted molecular weight: 48 kDa.
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| 特記事項 |
|---|
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WB
Use a concentration of 1 - 5 µg/ml. Predicted molecular weight: 48 kDa. |
ターゲット情報
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関連性
BCS1L (BCS1-like) is a chaperone necessary for the assembly of mitochondrial respiratory chain complex III. The protein does not contain a mitochondrial targeting sequence but experimental studies confirm that it is imported into mitochondria. Mutations in this gene are associated with mitochondrial complex III deficiency and the GRACILE syndrome. Two alternatively spliced transcripts encoding the same protein have been described. -
細胞内局在
Mitochondrial. Mitochondrion inner membrane. Single-pass membrane protein. -
参照データベース
- Entrez Gene: 617 Human
- Entrez Gene: 66821 Mouse
- Omim: 603647 Human
- SwissProt: Q9Y276 Human
- SwissProt: Q9CZP5 Mouse
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別名
- BCS 1 antibody
- BCS 1L antibody
- BCS antibody
see all
画像
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Western blot - Anti-BCS1L antibody (ab102808)Anti-BCS1L antibody (ab102808) at 5 µg/ml + Mouse spleen tissue lysate at 50 µg
Secondary
Goat anti-Mouse IgG HRP at 1/2500 dilution
Predicted band size: 48 kDa -
Western blot - Anti-BCS1L antibody (ab102808)All lanes : Anti-BCS1L antibody (ab102808) at 5 µg/ml
Lane 1 : BCS1L transfected 293T cell line lysate
Lane 2 : Non-transfected 293T cell line lysate
Lysates/proteins at 25 µg per lane.
Secondary
All lanes : Goat anti-Mouse IgG HRP at 1/2500 dilution
Predicted band size: 48 kDa
データシートおよび資料
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Datasheet download
参考文献 (2)
ab102808 は 2 報の論文で使用されています。
- Lobo-Jarne T et al. Human COX7A2L Regulates Complex III Biogenesis and Promotes Supercomplex Organization Remodeling without Affecting Mitochondrial Bioenergetics. Cell Rep 25:1786-1799.e4 (2018). PubMed: 30428348
- Chen X et al. Artesunate Activates the Intrinsic Apoptosis of HCT116 Cells through the Suppression of Fatty Acid Synthesis and the NF-?B Pathway. Molecules 22:N/A (2017). PubMed: 28786914
