製品の概要
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製品名Anti-Bcl 7A antibody
Bcl 7A 一次抗体 製品一覧 -
製品の詳細Goat polyclonal to Bcl 7A
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由来種Goat
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特異性This antibody is expected to recognize both reported isoforms (NP_066273.1; NP_001019979.1).
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アプリケーション適用あり: WBmore details
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種交差性交差種: Human
交差が予測される動物種: Mouse, Rat, Cow, Dog, Pig
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免疫原
Synthetic peptide: MKLEASQQNSEEM, corresponding to C terminal amino acids 219-231 of Human Bcl 7A.
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ポジティブ･コントロール
- Human lymph node lysate.
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特記事項This protein is similar to the actin-binding protein caldesmon.
製品の特性
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製品の状態Liquid
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保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
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バッファーPreservative: 0.02% Sodium Azide
Constituents: 0.5% BSA, Tris buffered saline, pH 7.3 -
Concentration information loading... -
精製度Immunogen affinity purified
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特記事項（精製）Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
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ポリ/モノポリクローナル
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アイソタイプIgG
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研究分野
関連製品
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Compatible Secondaries
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Immunizing Peptide (Blocking)
アプリケーション
Our Abpromise guarantee covers the use of ab1075 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB | Use a concentration of 1 - 3 µg/ml. Detects a band of approximately 26 kDa (predicted molecular weight: 25 kDa).Can be blocked with Human Bcl 7A peptide (ab22792). |
ターゲット情報
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関連疾患Note=Chromosomal aberrations involving BCL7A may be a cause of B-cell non-Hodgkin lymphoma. Three-way translocation t(8;14;12)(q24.1;q32.3;q24.1) with MYC and with immunoglobulin gene regions.
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配列類似性Belongs to the BCL7 family.
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翻訳後修飾Phosphorylated upon DNA damage, probably by ATM or ATR.
- Information by UniProt
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参照データベース
- Entrez Gene: 605 Human
- Entrez Gene: 77045 Mouse
- Entrez Gene: 360809 Rat
- Omim: 601406 Human
- SwissProt: Q4VC05 Human
- SwissProt: Q9CXE2 Mouse
- Unigene: 530970 Human
- Unigene: 151960 Mouse
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別名
- B cell CLL/lymphoma 7 antibody
- B cell CLL/lymphoma 7 protein family member A antibody
- B cell CLL/lymphoma 7A antibody
see all
画像
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Western blot - Anti-Bcl 7A antibody (ab1075)Anti-Bcl 7A antibody (ab1075) at 1 µg/ml + Human lymph node lysate (RIPA buffer) at 35 µg
Developed using the ECL technique.
Predicted band size: 25 kDa
Observed band size: 26 kDa (why is the actual band size different from the predicted?)
Primary incubated for 1 hour.
プロトコール
参考文献
ab1075 has not yet been referenced specifically in any publications.
レビューと Q&A
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"