Atropine, mAChR antagonist (ab145582)
Key features and details
- Potent, competitive, non-selective mAChR antagonist
- CAS Number: 51-55-8
- Purity: > 98%
- Soluble in water to 5 mM
- Form / State: Solid
- Source: Solanaceae sp.
製品の概要
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製品名
Atropine, mAChR antagonist -
製品の詳細
Potent, competitive, non-selective mAChR antagonist -
精製度
> 98% -
CAS 番号
51-55-8 -
構造式
製品の特性
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体系名
(8-Methyl-8-azabicyclo[3.2.1]octan-3-yl) 3-hydroxy-2-phenylpropanoate -
分子量
289.37 -
分子式
C17H23NO3 -
PubChem 登録番号
3661 -
保存方法
Store at Room Temperature. The product can be stored for up to 12 months. -
溶解性
Soluble in water to 5 mM -
使用に関する注意
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic, refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES 線形表記
CN1C2CCC1CC(C2)OC(=O)C(CO)C3=CC=CC=C3 -
由来
Solanaceae sp.
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研究分野
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (4)
ab145582 は 4 報の論文で使用されています。
- Tryon SC et al. Differential Regulation of Prelimbic and Thalamic Transmission to the Basolateral Amygdala by Acetylcholine Receptors. J Neurosci 43:722-735 (2023). PubMed: 36535767
- Huang H et al. M1 Macrophage Activated by Notch Signal Pathway Contributed to Ventilator-Induced Lung Injury in Chronic Obstructive Pulmonary Disease Model. J Surg Res 244:358-367 (2019). PubMed: 31323391
- Radzicki D et al. Loss of M1 Receptor Dependent Cholinergic Excitation Contributes to mPFC Deactivation in Neuropathic Pain. J Neurosci 37:2292-2304 (2017). PubMed: 28137966
- Wang YJ et al. The Analgesic Effects of (5R,6R)6-(3-Propylthio-1,2,5-thiadiazol-4-yl)-1-azabicyclo[3.2.1] Octane on a Mouse Model of Neuropathic Pain. Anesth Analg 124:1330-1338 (2017). PubMed: 28002166