Anti-ATP11A 抗体 (ab105351)
Key features and details
- Rabbit polyclonal to ATP11A
- Suitable for: WB, ICC
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-ATP11A antibody -
製品の詳細
Rabbit polyclonal to ATP11A -
由来種
Rabbit -
特異性
ab105351 is predicted to not cross react with AT11B. At least two isoforms of ATP11A are known to exist; this antibody will recognize both. -
アプリケーション
適用あり: WB, ICCmore details -
種交差性
交差種: Human -
免疫原
Synthetic peptide corresponding to Human ATP11A (N terminal).
Database link: NP_115565 -
ポジティブ・コントロール
- WB: K562 cell lysate ICC: K562 cells
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C. -
バッファー
pH: 7.2
Preservative: 0.02% Sodium azide
Constituent: PBS -
Concentration information loading...
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精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab105351の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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WB |
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 130 kDa.
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ICC |
Use a concentration of 10 - 20 µg/ml.
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特記事項 |
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WB
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 130 kDa. |
ICC
Use a concentration of 10 - 20 µg/ml. |
ターゲット情報
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機能
Catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules (Probable). May be involved in the uptake of farnesyltransferase inhibitor drugs, such as lonafarnib. -
配列類似性
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. -
細胞内局在
Cell membrane. Early endosome. Recycling endosome. Endoplasmic reticulum. Exit from the endoplasmic reticulum requires the presence of TMEM30A, but not TMEM30B. In the presence of TMEM30A, predominantly located in the plasma membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 23250 Human
- Omim: 605868 Human
- SwissProt: P98196 Human
- Unigene: 29189 Human
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製品の状態
P-type ATPases, such as ATP11A, are phosphorylated in their intermediate state and drive uphill transport of ions across membranes. -
別名
- AT11A antibody
- AT11A_HUMAN antibody
- Atp11a antibody
see all
画像
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Immunofluorescence of ATP11A in K562 cells with ab105351 at 20 ug/mL.
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All lanes : Anti-ATP11A antibody (ab105351) at 1 µg/ml
Lane 1 : K562 cell lysate
Lane 2 : K562 cell lysate with blocking peptide
Lysates/proteins at 15 µg per lane.
Predicted band size: 130 kDa -
ab105351, at 10 µg/ml, staining ATP11A in K562 cells by Immunocytochemistry.
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (0)
ab105351 は論文での使用が確認できていません。