Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EPR7040] to Aquaporin 4 - BSA and Azide free
- Suitable for: IHC-P
- Reacts with: Rat, Human
製品名Anti-Aquaporin 4 antibody [EPR7040] - BSA and Azide free
Aquaporin 4 一次抗体 製品一覧
製品の詳細Rabbit monoclonal [EPR7040] to Aquaporin 4 - BSA and Azide free
アプリケーション適用あり: IHC-Pmore details
種交差性交差種: Rat, Human
Synthetic peptide within Human Aquaporin 4 aa 300-400. The exact sequence is proprietary.
ab248213 is the carrier-free version of ab128906 This format is designed for use in antibody labeling, including fluorochromes, metal isotopes, oligonucleotides, enzymes.
Our carrier-free formats are supplied in a buffer free of BSA, sodium azide and glycerol for higher conjugation efficiency.
Use our conjugation kits for antibody conjugates that are ready-to-use in as little as 20 minutes with <1 minute hands-on-time and 100% antibody recovery: available for fluorescent dyes, HRP, biotin and gold.
Ab248213 is compatible with the Maxpar® Antibody Labeling Kit from Fluidigm.
Maxpar® is a trademark of Fluidigm Canada Inc.
Mouse: We have preliminary internal testing data to indicate this antibody may not react with this species. Please contact us for more information.
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
保存方法Shipped at 4°C. Store at +4°C. Do Not Freeze.
解離定数（KD 値）KD = 2.60 x 10 -12 M Learn more about KD
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Our Abpromise guarantee covers the use of ab248213 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||Use at an assay dependent concentration. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.|
機能Forms a water-specific channel. Osmoreceptor which regulates body water balance and mediates water flow within the central nervous system.
組織特異性Brain - muscle >> heart, kidney, lung, and trachea.
配列類似性Belongs to the MIP/aquaporin (TC 1.A.8) family.
ドメインAquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).
翻訳後修飾Phosphorylation by PKC at Ser-180 reduces conductance by 50%. Phosphorylation by PKG at Ser-111 in response to glutamats increases conductance by 40%.
- Information by UniProt
- AQP 4 antibody
- AQP-4 antibody
- AQP4 antibody
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.