Anti-Apoptosis enhancing nuclease 抗体 (ab97915)
Key features and details
- Rabbit polyclonal to Apoptosis enhancing nuclease
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-Apoptosis enhancing nuclease antibody -
製品の詳細
Rabbit polyclonal to Apoptosis enhancing nuclease -
由来種
Rabbit -
アプリケーション
適用あり: WB, IHC-Pmore details -
種交差性
交差種: Human -
免疫原
Synthetic peptide, corresponding to a region within amino acids 236-297 of Apoptosis enhancing nuclease (NP_073604).
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ポジティブ・コントロール
- HeLa, HepG2 or MOLT4 cell lines.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
バッファー
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 10% Glycerol (glycerin, glycerine) -
Concentration information loading...
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精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Positive Controls
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab97915の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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WB |
1/500 - 1/3000. Predicted molecular weight: 36 kDa.
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IHC-P |
1/100 - 1/250.
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特記事項 |
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WB
1/500 - 1/3000. Predicted molecular weight: 36 kDa. |
IHC-P
1/100 - 1/250. |
ターゲット情報
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機能
Exonuclease with activity against single- and double-stranded DNA and RNA. Mediates p53-induced apoptosis. When induced by p53 following DNA damage, digests double-stranded DNA to form single-stranded DNA and amplifies DNA damage signals, leading to enhancement of apoptosis. -
配列類似性
Contains 1 exonuclease domain. -
細胞内局在
Nucleus. Nucleus > nucleolus. Localized predomintly in the nucleolus. Translocates from the nucleolus to the nucleoplasm upon apoptosis induction. - Information by UniProt
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参照データベース
- Entrez Gene: 64782 Human
- Omim: 610177 Human
- SwissProt: Q8WTP8 Human
- Unigene: 436102 Human
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別名
- Aen antibody
- AEN_HUMAN antibody
- apoptosis enhancing nuclease antibody
see all
画像
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Anti-Apoptosis enhancing nuclease antibody (ab97915) at 1/1000 dilution + HeLa whole cell lysate at 30 µg
Predicted band size: 36 kDa
10% SDS PAGE -
ab97915, at 1/100 dilution, staining Apoptosis enhancing nuclease in Cal27 xenograft tissue by Immunohistochemistry. Formalin-fixed, paraffin-embedded section.
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (0)
ab97915 は論文での使用が確認できていません。