Anti-APC2 抗体 (ab106600)
Key features and details
- Rabbit polyclonal to APC2
- Suitable for: ICC/IF, WB, ICC
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-APC2 antibody
APC2 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to APC2 -
由来種
Rabbit -
特異性
ab106600 is predicted to not cross-react with other Apc family members. At least four isoforms of Apc2 are known to exist. -
アプリケーション
適用あり: ICC/IF, WB, ICCmore details -
種交差性
交差種: Human -
免疫原
Synthetic peptide corresponding to Human APC2 (internal sequence).
Database link: O95996 -
ポジティブ･コントロール
- HeLa cells and cell lysate
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at 4°C (stable for up to 12 months). -
バッファー
pH: 7.2
Preservative: 0.02% Sodium azide
Constituent: PBS -
Concentration information loading... -
精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab106600の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| ICC/IF |
Use a concentration of 20 µg/ml.
|
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| WB |
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 244 kDa.
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| ICC |
Use a concentration of 5 µg/ml.
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| 特記事項 |
|---|
|
ICC/IF
Use a concentration of 20 µg/ml. |
|
WB
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 244 kDa. |
|
ICC
Use a concentration of 5 µg/ml. |
ターゲット情報
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機能
Promotes rapid degradation of CTNNB1 and may function as a tumor suppressor. May function in Wnt signaling. -
組織特異性
Widely expressed (at protein level). Specifically expressed in the CNS. -
配列類似性
Belongs to the adenomatous polyposis coli (APC) family.
Contains 6 ARM repeats. -
発生段階
Expressed in fetal brain. -
細胞内局在
Cytoplasm, cytoskeleton. Golgi apparatus. Cytoplasm. Cytoplasm, perinuclear region. Associated with actin filaments (PubMed:11691822). Associated with microtubule network (PubMed:10644998, PubMed:11691822). - Information by UniProt
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参照データベース
- Entrez Gene: 10297 Human
- SwissProt: O95996 Human
- Unigene: 446376 Human
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別名
- Adenomatous polyposis coli protein 2 antibody
- Adenomatous polyposis coli protein-like antibody
- APC-like antibody
see all
画像
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Western blot - Anti-APC2 antibody (ab106600)Lane 1 : Anti-APC2 antibody (ab106600) at 1 µg/ml
Lane 2 : Anti-APC2 antibody (ab106600) at 2 µg/ml
All lanes : HeLa cell lysate
Lysates/proteins at 15 µg per lane.
Predicted band size: 244 kDa -
Immunocytochemistry/ Immunofluorescence - Anti-APC2 antibody (ab106600)Immunofluorescence of APC2 in HeLa cells with ab106600 at 20 ug/mL.
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Immunocytochemistry - Anti-APC2 antibody (ab106600)Immunocytochemical analysis of ab106600 at 5 µg/ml in HeLa cells.
プロトコール
データシートおよび資料
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Datasheet download
参考文献 (0)
ab106600 は論文での使用が確認できていません。
