APC Anti-TCR alpha + TCR beta 抗体 [IP26] (ab99859)
Key features and details
- APC Mouse monoclonal [IP26] to TCR alpha + TCR beta
- Suitable for: Flow Cyt
- Reacts with: Human
- Conjugation: APC. Ex: 645nm, Em: 660nm
- Isotype: IgG1
製品の概要
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製品名
APC Anti-TCR alpha + TCR beta antibody [IP26]
TCR alpha + TCR beta 一次抗体 製品一覧 -
製品の詳細
APC Mouse monoclonal [IP26] to TCR alpha + TCR beta -
由来種
Mouse -
標識
APC. Ex: 645nm, Em: 660nm -
特異性
Recognizes a monomorphic determinant of TCR alpha/beta, the dominant subtype of T cell receptor expressed in human peripheral blood. -
アプリケーション
適用あり: Flow Cytmore details -
種交差性
交差種: Human -
免疫原
Human TCR alpha + TCR beta
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ポジティブ・コントロール
- Human peripheral blood T cells
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特記事項
Short term exposure to room temperature should not affect the quality of the reagent. However, if reagent is stored under any conditions other than those specified, the conditions must be verified by the user.
The purified antibody is conjugated with Allophycocyanin (APC) under optimum conditions. No reconstitution is necessary.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C. -
バッファー
pH: 7.4
Preservative: 0.097% Sodium azide
Constituents: 0.2% BSA, PBS -
Concentration information loading...
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精製度
Size exclusion -
特記事項(精製)
The unconjugated antibody was purified by protein A (G) affinity chromatography (>95% by SDS-PAGE). After conjugation, the antibody was purified by size exclusion chromatography and adjusted for direct use. -
ポリ/モノ
モノクローナル -
クローン名
IP26 -
アイソタイプ
IgG1 -
研究分野
関連製品
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Alternative Versions
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab99859の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
---|---|---|
Flow Cyt |
Use at an assay dependent concentration.
or 100 µl of whole blood. |
特記事項 |
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Flow Cyt
Use at an assay dependent concentration. or 100 µl of whole blood. |
ターゲット情報
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関連性
The receptors on T cells consist of immunoglobulin like integral membrane glycoproteins containing 2 polypeptide subunits, alpha and beta, of similar molecular weight, 40 to 55 kD in the human. Like the immunoglobulins of the B cells, each T cell receptor subunit has, external to the cell membrane, an N terminal variable domain and a C terminal constant domain. T cell receptors recognise foreign antigens which have been processed as small peptides and bound to major histocompatibility complex molecules at the surface of antigen presenting cells. Each T cell receptor is a dimer consisting of one alpha and one beta chain or one delta and one gamma chain. In a single cell, the T cell receptor loci are rearranged and expressed in the order delta, gamma, beta, and alpha. If both delta and gamma rearrangements produce functional chains, the cell expresses delta and gamma. If not, the cell proceeds to rearrange the beta and alpha loci. -
細胞内局在
Type I membrane protein. -
参照データベース
- Entrez Gene: 6955 Human
- Entrez Gene: 6957 Human
- Omim: 186880 Human
- Omim: 186930 Human
- SwissProt: P01848 Human
- SwissProt: P04435 Human
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別名
- FLJ22602 antibody
- MGC117436 antibody
- MGC22624 antibody
see all
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (1)
ab99859 は 1 報の論文で使用されています。
- Kuttruff S et al. NKp80 defines and stimulates a reactive subset of CD8 T cells. Blood 113:358-69 (2009). PubMed: 18922855