APC Anti-P Glycoprotein 抗体 [UIC2] (ab272340)
![Flow Cytometry - APC Anti-P Glycoprotein antibody [UIC2] (ab272340)](https://www.abcam.co.jp/ps/products/272/ab272340/Images/ab272340-387916-Mouse-monoclonal-UIC2-P-Glycoprotein-Allophycocyanin-flow-cytometry-hepg2-human.jpg "Flow Cytometry - APC Anti-P Glycoprotein antibody [UIC2] (ab272340)")
Key features and details
- APC Mouse monoclonal [UIC2] to P Glycoprotein
- Suitable for: Flow Cyt
- Reacts with: Human
- Conjugation: APC. Ex: 645nm, Em: 660nm
- Isotype: IgG2a
製品の概要
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製品名
APC Anti-P Glycoprotein antibody [UIC2]
P Glycoprotein 一次抗体 製品一覧 -
製品の詳細
APC Mouse monoclonal [UIC2] to P Glycoprotein -
由来種
Mouse -
標識
APC. Ex: 645nm, Em: 660nm -
Tested Applications & Species
See all applications and species dataApplication Species Flow Cyt Human
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免疫原
Tissue, cells or virus corresponding to P Glycoprotein. NIH/3T3 cells transfected with human P Glycoprotein cDNA.
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ポジティブ･コントロール
- Flow Cyt: HepG2 cell suspension. Human peripheral whole blood cells.
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C. Store In the Dark. -
バッファー
pH: 7.4
Preservative: 0.0975% Sodium azide
Constituent: PBS -
Concentration information loading... -
精製度
Size exclusion -
特記事項（精製）
Purified from TCS. -
ポリ/モノ
モノクローナル -
クローン名
UIC2 -
アイソタイプ
IgG2a -
軽鎖の種類
kappa -
研究分野
関連製品
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Alternative Versions
アプリケーション
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab272340 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Tested applications are guaranteed to work and covered by our Abpromise guarantee.
Predicted to work for this combination of applications and species but not guaranteed.
Does not work for this combination of applications and species.
| アプリケーション | Species |
|---|---|
| Flow Cyt |
Human
|
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| Flow Cyt |
Use at an assay dependent concentration.
The reagent is designed for analysis of human blood cells using 10 μl reagent / 100 μl of whole blood or 106 cells in a suspension. |
| 特記事項 |
|---|
|
Flow Cyt
Use at an assay dependent concentration. The reagent is designed for analysis of human blood cells using 10 μl reagent / 100 μl of whole blood or 106 cells in a suspension. |
ターゲット情報
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機能
Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells. -
組織特異性
Expressed in liver, kidney, small intestine and brain. -
関連疾患
Genetic variations in ABCB1 are associated with susceptibility to inflammatory bowel disease type 13 (IBD13) [MIM:612244]. Inflammatory bowel disease is characterized by a chronic relapsing intestinal inflammation. It is subdivided into Crohn disease and ulcerative colitis phenotypes. Crohn disease may involve any part of the gastrointestinal tract, but most frequently the terminal ileum and colon. Bowel inflammation is transmural and discontinuous; it may contain granulomas or be associated with intestinal or perianal fistulas. In contrast, in ulcerative colitis, the inflammation is continuous and limited to rectal and colonic mucosal layers; fistulas and granulomas are not observed. Both diseases include extraintestinal inflammation of the skin, eyes, or joints. Crohn disease and ulcerative colitis are commonly classified as autoimmune diseases. -
配列類似性
Belongs to the ABC transporter superfamily. ABCB family. Multidrug resistance exporter (TC 3.A.1.201) subfamily.
Contains 2 ABC transmembrane type-1 domains.
Contains 2 ABC transporter domains. -
細胞内局在
Membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 5243 Human
- Omim: 171050 Human
- SwissProt: P08183 Human
- Unigene: 489033 Human
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別名
- ABC20 antibody
- ABCB1 antibody
- ATP binding cassette, sub family B (MDR/TAP), member 1 antibody
see all
画像
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Flow Cytometry - APC Anti-P Glycoprotein antibody [UIC2] (ab272340)
Flow cytometry surface staining pattern of HepG2 (Human liver hepatocellular carcinoma cell line) cell suspension stained using ab272340 at 10 μl reagent per milion cells in 100 μl of cell suspension. P Glycoprotein also known as CD243.
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![Flow Cytometry - APC Anti-P Glycoprotein antibody [UIC2] (ab272340)](https://www.abcam.co.jp/ps/products/272/ab272340/Images/ab272340-387915-Mouse-monoclonal-UIC2-P-Glycoprotein-Allophycocyanin-flow-cytometry-human-peripheral-whole-blood-cells.jpg)
Flow Cytometry - APC Anti-P Glycoprotein antibody [UIC2] (ab272340)Separation of HepG2 (Human liver hepatocellular carcinoma cell line) cells (red-filled) from human peripheral whole blood cells (black-dashed) in flow cytometry analysis (surface staining) stained using ab272340 at 10 μl reagent per milion cells in 100 μl of cell suspension. P Glycoprotein also known as CD243.
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
参考文献 (0)
ab272340 は論文での使用が確認できていません。
