APC Anti-Integrin alpha 4/CD49D 抗体 [9F10] (ab272269)
![Flow Cytometry - APC Anti-Integrin alpha 4/CD49D antibody [9F10] (ab272269)](https://www.abcam.co.jp/ps/products/272/ab272269/Images/ab272269-387784-Mouse-monoclonal-9F10-to-Integrin-alpha-4-CD49D-flow.jpg "Flow Cytometry - APC Anti-Integrin alpha 4/CD49D antibody [9F10] (ab272269)")
Key features and details
- APC Mouse monoclonal [9F10] to Integrin alpha 4/CD49D
- Suitable for: Flow Cyt
- Reacts with: Human
- Conjugation: APC. Ex: 645nm, Em: 660nm
- Isotype: IgG1
製品の概要
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製品名
APC Anti-Integrin alpha 4/CD49D antibody [9F10]
Integrin alpha 4/CD49D 一次抗体 製品一覧 -
製品の詳細
APC Mouse monoclonal [9F10] to Integrin alpha 4/CD49D -
由来種
Mouse -
標識
APC. Ex: 645nm, Em: 660nm -
アプリケーション
適用あり: Flow Cytmore details -
種交差性
交差種: Human -
免疫原
The details of the immunogen for this antibody are not available.
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ポジティブ･コントロール
- Flow cyt: Human peripheral blood lymphocytes.
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C. Store In the Dark. -
バッファー
pH: 7.20
Preservative: 0.09% Sodium azide
Constituents: 0.12% Monobasic dihydrogen sodium phosphate, 0.87% Sodium chloride, 0.1% Gelatin -
Concentration information loading... -
精製度
Affinity purified -
特記事項（精製）
Purified from tissue culture supernatant. -
ポリ/モノ
モノクローナル -
クローン名
9F10 -
アイソタイプ
IgG1 -
軽鎖の種類
kappa -
研究分野
関連製品
アプリケーション
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab272269 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| Flow Cyt |
Use 5µl for 105-8 cells.
In a volume of 100 μL. |
| 特記事項 |
|---|
|
Flow Cyt
Use 5µl for 105-8 cells. In a volume of 100 μL. |
ターゲット情報
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機能
Integrins alpha-4/beta-1 (VLA-4) and alpha-4/beta-7 are receptors for fibronectin. They recognize one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. They are also receptors for VCAM1. Integrin alpha-4/beta-1 recognizes the sequence Q-I-D-S in VCAM1. Integrin alpha-4/beta-7 is also a receptor for MADCAM1. It recognizes the sequence L-D-T in MADCAM1. On activated endothelial cells integrin VLA-4 triggers homotypic aggregation for most VLA-4-positive leukocyte cell lines. It may also participate in cytolytic T-cell interactions with target cells. -
配列類似性
Belongs to the integrin alpha chain family.
Contains 7 FG-GAP repeats. -
ドメイン
The SG1 motif is involved in binding to chondroitin sulfate glycosaminoglycan and cell adhesion. -
翻訳後修飾
Phosphorylation on Ser-1027 inhibits PXN binding. -
細胞内局在
Membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 3676 Human
- Omim: 192975 Human
- SwissProt: P13612 Human
- Unigene: 440955 Human
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別名
- 269C wild type antibody
- Antigen CD49D, alpha 4 subunit of VLA 4 receptor antibody
- CD49 antigen like family member D antibody
see all
画像
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Flow Cytometry - APC Anti-Integrin alpha 4/CD49D antibody [9F10] (ab272269)
Human peripheral blood lymphocytes were stained with 5 uL (0.25 ug) of ab272269 (solid line) or 0.25 ug APC Mouse IgG1 isotype control (dashed line).
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
参考文献 (0)
ab272269 は論文での使用が確認できていません。
