APC Anti-IL-4 抗体 [11B11] (ab95715)
![Flow Cytometry (Intracellular) - APC Anti-IL-4 antibody [11B11] (ab95715)](https://www.abcam.co.jp/ps/products/95/ab95715/Images/ab95715-277237-anti-il-4-antibody-11b11-allophycocyanin-flow-cytometry.jpg "Flow Cytometry (Intracellular) - APC Anti-IL-4 antibody [11B11] (ab95715)")
Key features and details
- APC Rat monoclonal [11B11] to IL-4
- Suitable for: Flow Cyt (Intra)
- Reacts with: Mouse
- Conjugation: APC. Ex: 645nm, Em: 660nm
- Isotype: IgG1
Related conjugates and formulations
製品の概要
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製品名
APC Anti-IL-4 antibody [11B11]
IL-4 一次抗体 製品一覧 -
製品の詳細
APC Rat monoclonal [11B11] to IL-4 -
由来種
Rat -
標識
APC. Ex: 645nm, Em: 660nm -
アプリケーション
適用あり: Flow Cyt (Intra)more details -
種交差性
交差種: Mouse -
免疫原
Full length native protein (purified) corresponding to Mouse IL-4.
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ポジティブ･コントロール
- Mouse lymphoid cells: Flow Cyt (Intra).
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C. Do Not Freeze. Store In the Dark. -
バッファー
pH: 7.20
Preservative: 0.09% Sodium azide
Constituents: 0.88% Sodium chloride, 0.12% Monobasic dihydrogen sodium phosphate, 0.1% Gelatin -
Concentration information loading... -
精製度
Affinity purified -
ポリ/モノ
モノクローナル -
クローン名
11B11 -
アイソタイプ
IgG1 -
軽鎖の種類
kappa -
研究分野
関連製品
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Alternative Versions
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab95715の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| Flow Cyt (Intra) |
Use at an assay dependent concentration.
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| 特記事項 |
|---|
|
Flow Cyt (Intra)
Use at an assay dependent concentration. |
ターゲット情報
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機能
Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. -
関連疾患
Genetic variations in IL4 may be a cause of susceptibility to ischemic stroke (ISCHSTR) [MIM:601367]; also known as cerebrovascular accident or cerebral infarction. A stroke is an acute neurologic event leading to death of neural tissue of the brain and resulting in loss of motor, sensory and/or cognitive function. Ischemic strokes, resulting from vascular occlusion, is considered to be a highly complex disease consisting of a group of heterogeneous disorders with multiple genetic and environmental risk factors. -
配列類似性
Belongs to the IL-4/IL-13 family. -
細胞内局在
Secreted. - Information by UniProt
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参照データベース
- Entrez Gene: 16189 Mouse
- SwissProt: P07750 Mouse
- Unigene: 276360 Mouse
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別名
- B cell growth factor 1 antibody
- B cell IgG differentiation factor antibody
- B Cell Stimulatory Factor 1 antibody
see all
画像
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Flow Cytometry (Intracellular) - APC Anti-IL-4 antibody [11B11] (ab95715)
Mouse lymphoid cells were stimulated in the presence of a protein transport inhibitor. Cells were then fixed, permeabilized , stained with FITC-conjugated anti-CD4and intracellularly with 0.5µgab95715 (right) or 0.5µg APC-conjugated rat IgG1 isotype control (left).
データシートおよび資料
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Datasheet download
参考文献 (0)
ab95715 は論文での使用が確認できていません。
