APC Anti-CD45RA 抗体 [HI100] (ab272270)
![Flow Cytometry - APC Anti-CD45RA antibody [HI100] (ab272270)](https://www.abcam.co.jp/ps/products/272/ab272270/Images/ab272270-387054-anti-CD45RA-human-antibody-APC-conjugated-hi100-flow.JPG "Flow Cytometry - APC Anti-CD45RA antibody [HI100] (ab272270)")
Key features and details
- APC Mouse monoclonal [HI100] to CD45RA
- Suitable for: Flow Cyt
- Reacts with: Human
- Conjugation: APC. Ex: 645nm, Em: 660nm
- Isotype: IgG2b
製品の概要
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製品名
APC Anti-CD45RA antibody [HI100]
CD45RA 一次抗体 製品一覧 -
製品の詳細
APC Mouse monoclonal [HI100] to CD45RA -
由来種
Mouse -
標識
APC. Ex: 645nm, Em: 660nm -
アプリケーション
適用あり: Flow Cytmore details -
種交差性
交差種: Human
交差が予測される動物種: Chimpanzee
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免疫原
The details of the immunogen for this antibody are not available.
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ポジティブ･コントロール
- Flow Cyt: Human peripheral blood lymphocytes.
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C. Store In the Dark. -
バッファー
pH: 7.20
Preservative: 0.09% Sodium azide
Constituents: 0.12% Monobasic dihydrogen sodium phosphate, 0.87% Sodium chloride, 0.1% Gelatin -
Concentration information loading... -
精製度
Affinity purified -
特記事項（精製）
Purified from tissue culture supernatant. -
ポリ/モノ
モノクローナル -
クローン名
HI100 -
アイソタイプ
IgG2b -
軽鎖の種類
kappa -
研究分野
関連製品
アプリケーション
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab272270 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| Flow Cyt |
Use 5µl for 105-8 cells.
In a sample volume of 100 μL |
| 特記事項 |
|---|
|
Flow Cyt
Use 5µl for 105-8 cells. In a sample volume of 100 μL |
ターゲット情報
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機能
Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. Dephosphorylates LYN, and thereby modulates LYN activity. -
関連疾患
Severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive
Multiple sclerosis -
配列類似性
Belongs to the protein-tyrosine phosphatase family. Receptor class 1/6 subfamily.
Contains 2 fibronectin type-III domains.
Contains 2 tyrosine-protein phosphatase domains. -
ドメイン
The first PTPase domain interacts with SKAP1. -
翻訳後修飾
Heavily N- and O-glycosylated. -
細胞内局在
Membrane. Membrane raft. Colocalized with DPP4 in membrane rafts. - Information by UniProt
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参照データベース
- Entrez Gene: 457607 Chimpanzee
- Entrez Gene: 5788 Human
- Omim: 151460 Human
- SwissProt: P08575 Human
- Unigene: 654514 Human
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別名
- B220 antibody
- CD45 antibody
- CD45 antigen antibody
see all
画像
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Flow Cytometry - APC Anti-CD45RA antibody [HI100] (ab272270)
Human peripheral blood lymphocytes were stained with 5 uL (0.125 ug) ab272270 (solid line) or 0.125 ug APC Mouse IgG2b isotype control (dashed line).
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
参考文献 (0)
ab272270 は論文での使用が確認できていません。
