APC Anti-CD20 抗体 [2H7] (ab272272)
Key features and details
- APC Mouse monoclonal [2H7] to CD20
- Suitable for: Flow Cyt
- Reacts with: Human
- Conjugation: APC. Ex: 645nm, Em: 660nm
- Isotype: IgG2b
製品の概要
-
製品名
APC Anti-CD20 antibody [2H7]
CD20 一次抗体 製品一覧 -
製品の詳細
APC Mouse monoclonal [2H7] to CD20 -
由来種
Mouse -
標識
APC. Ex: 645nm, Em: 660nm -
アプリケーション
適用あり: Flow Cytmore details -
種交差性
交差種: Human
交差が予測される動物種: Chimpanzee, Baboon, Cynomolgus monkey, Rhesus monkey -
免疫原
Tissue, cells or virus corresponding to CD20.
-
ポジティブ・コントロール
- Flow Cyt: Human peripheral blood lymphocytes.
-
特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
-
製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C. Store In the Dark. -
バッファー
pH: 7.20
Preservative: 0.09% Sodium azide
Constituents: 0.12% Monobasic dihydrogen sodium phosphate, 0.87% Sodium chloride, 0.1% Gelatin -
Concentration information loading...
-
精製度
Affinity purified -
特記事項(精製)
Purified from tissue culture supernatant. -
ポリ/モノ
モノクローナル -
クローン名
2H7 -
アイソタイプ
IgG2b -
軽鎖の種類
kappa -
研究分野
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab272272の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
---|---|---|
Flow Cyt |
Use 5µl for 105-8 cells.
In a volume of 100 µL. |
特記事項 |
---|
Flow Cyt
Use 5µl for 105-8 cells. In a volume of 100 µL. |
ターゲット情報
-
機能
This protein may be involved in the regulation of B-cell activation and proliferation. -
組織特異性
Expressed on B-cells. -
関連疾患
Defects in MS4A1 are the cause of immunodeficiency common variable type 5 (CVID5) [MIM:613495]; also called antibody deficiency due to CD20 defect. CVID5 is a primary immunodeficiency characterized by antibody deficiency, hypogammaglobulinemia, recurrent bacterial infections and an inability to mount an antibody response to antigen. The defect results from a failure of B-cell differentiation and impaired secretion of immunoglobulins; the numbers of circulating B cells is usually in the normal range, but can be low. -
配列類似性
Belongs to the MS4A family. -
翻訳後修飾
Phosphorylated. Might be functionally regulated by protein kinase(s). -
細胞内局在
Membrane. - Information by UniProt
-
参照データベース
- Entrez Gene: 101011366 Baboon
- Entrez Gene: 451223 Chimpanzee
- Entrez Gene: 102118491 Cynomolgus monkey
- Entrez Gene: 931 Human
- Entrez Gene: 696843 Rhesus monkey
- Omim: 112210 Human
- SwissProt: P11836 Human
- Unigene: 712553 Human
-
別名
- APY antibody
- ATOPY antibody
- B lymphocyte antigen CD20 antibody
see all
画像
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
-
Datasheet download
参考文献 (0)
ab272272 は論文での使用が確認できていません。