APC Anti-CD20 抗体 [2H7] (ab272272)
![Flow Cytometry - APC Anti-CD20 antibody [2H7] (ab272272)](https://www.abcam.co.jp/ps/products/272/ab272272/Images/ab272272-387056-anti-CD20-human-antibody-APC-conjugated-2h7-flow.JPG "Flow Cytometry - APC Anti-CD20 antibody [2H7] (ab272272)")
Key features and details
- APC Mouse monoclonal [2H7] to CD20
- Suitable for: Flow Cyt
- Reacts with: Human
- Conjugation: APC. Ex: 645nm, Em: 660nm
- Isotype: IgG2b
製品の概要
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製品名
APC Anti-CD20 antibody [2H7]
CD20 一次抗体 製品一覧 -
製品の詳細
APC Mouse monoclonal [2H7] to CD20 -
由来種
Mouse -
標識
APC. Ex: 645nm, Em: 660nm -
アプリケーション
適用あり: Flow Cytmore details -
種交差性
交差種: Human
交差が予測される動物種: Chimpanzee, Baboon, Cynomolgus monkey, Rhesus monkey
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免疫原
The details of the immunogen for this antibody are not available.
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ポジティブ･コントロール
- Flow Cyt: Human peripheral blood lymphocytes.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing the problem with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation.
One factor contributing to the crisis is the use of antibodies that are not suitable. This can lead to misleading results and the use of incorrect data informing project assumptions and direction. To help address this challenge, we have introduced an application and species grid on our primary antibody datasheets to make it easy to simplify identification of the right antibody for your needs.
Learn more here.
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C. Store In the Dark. -
バッファー
pH: 7.20
Preservative: 0.09% Sodium azide
Constituents: 0.12% Monobasic dihydrogen sodium phosphate, 0.87% Sodium chloride, 0.1% Gelatin -
Concentration information loading... -
精製度
Affinity purified -
特記事項（精製）
Purified from tissue culture supernatant. -
ポリ/モノ
モノクローナル -
クローン名
2H7 -
アイソタイプ
IgG2b -
軽鎖の種類
kappa -
研究分野
関連製品
アプリケーション
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab272272 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| Flow Cyt |
Use 5µl for 105-8 cells.
In a volume of 100 μL. |
| 特記事項 |
|---|
|
Flow Cyt
Use 5µl for 105-8 cells. In a volume of 100 μL. |
ターゲット情報
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機能
This protein may be involved in the regulation of B-cell activation and proliferation. -
組織特異性
Expressed on B-cells. -
関連疾患
Defects in MS4A1 are the cause of immunodeficiency common variable type 5 (CVID5) [MIM:613495]; also called antibody deficiency due to CD20 defect. CVID5 is a primary immunodeficiency characterized by antibody deficiency, hypogammaglobulinemia, recurrent bacterial infections and an inability to mount an antibody response to antigen. The defect results from a failure of B-cell differentiation and impaired secretion of immunoglobulins; the numbers of circulating B cells is usually in the normal range, but can be low. -
配列類似性
Belongs to the MS4A family. -
翻訳後修飾
Phosphorylated. Might be functionally regulated by protein kinase(s). -
細胞内局在
Membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 101011366 Baboon
- Entrez Gene: 451223 Chimpanzee
- Entrez Gene: 102118491 Cynomolgus monkey
- Entrez Gene: 931 Human
- Entrez Gene: 696843 Rhesus monkey
- Omim: 112210 Human
- SwissProt: P11836 Human
- Unigene: 712553 Human
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別名
- APY antibody
- ATOPY antibody
- B lymphocyte antigen CD20 antibody
see all
画像
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Flow Cytometry - APC Anti-CD20 antibody [2H7] (ab272272)
Human peripheral blood lymphocytes were stained with FITC Anti-Human CD3 and 5 uL (0.125 ug) ab272272 (right panel) or 0.125 ug APC Mouse IgG2b isotype control (left panel).
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (0)
ab272272 は論文での使用が確認できていません。