Anti-Annexin V/ANXA5 抗体 (ab14196)
Key features and details
- Rabbit polyclonal to Annexin V/ANXA5
- Suitable for: IHC-P, IHC-Fr, IHC-FoFr, ICC/IF, WB, Flow Cyt
- Reacts with: Mouse, Rat, Human
- Isotype: IgG
リコンビナント抗体で、ロット間での高い再現性を実現
- 異なるロット間での安定した再現性
- 容易なスケールアップ
- 評価試験による特異性の確認済み
- 倫理基準に準拠 - アニマル・フリーの生産
製品の概要
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製品名
Anti-Annexin V/ANXA5 antibody
Annexin V/ANXA5 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to Annexin V/ANXA5 -
由来種
Rabbit -
アプリケーション
適用あり: IHC-P, IHC-Fr, IHC-FoFr, ICC/IF, WB, Flow Cytmore details -
種交差性
交差種: Mouse, Rat, Human -
免疫原
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特記事項
This product is manufactured by BioVision, an Abcam company and was previously called 3357 Annexin V Antibody.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
バッファー
Preservative: 0.03% Proclin 300
Constituents: PBS, 30% Glycerol (glycerin, glycerine), 0.5% BSA, 0.015% EDTA -
Concentration information loading... -
精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Immunizing Peptide (Blocking)
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Isotype control
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Recombinant Protein
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Related Products
- Annexin V/ANXA5-FITC Apoptosis Detection Reagent (500X) (ab14082)
- Propidium Iodide (ab14083)
- 10X Annexin V/ANXA5 Binding Buffer (ab14084)
- Annexin V-FITC Apoptosis Staining / Detection Kit (ab14085)
- Annexin V-Cy3 Apoptosis Staining / Detection Kit (ab14142)
- Annexin V/ANXA5-Cy3 Apoptosis Staining / Detection Reagent (ab14143)
- Annexin V-Cy3 Apoptosis Staining / Detection Kit with SYTOX (ab14144)
- Annexin V/ANXA5-Cy5 Apoptosis Staining / Detection Reagent (ab14147)
- Annexin V-Cy5 Apoptosis Staining / Detection Kit (ab14150)
- Annexin V-EGFP Apoptosis Staining / Detection Reagent (ab14152)
- Annexin V-EGFP Apoptosis Staining / Detection Kit (ab14153)
- Annexin V/ANXA5-PE Apoptosis Staining / Detection Reagent (ab14154)
- Annexin V-PE Apoptosis Staining / Detection Kit (ab14155)
- Annexin V-PE-Cy5 Apoptosis Staining / Detection Kit (ab14159)
- Annexin V/ANXA5-Biotin Apoptosis Staining / Detection Reagent (ab14165)
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab14196の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| IHC-P | (3) |
Use at an assay dependent concentration.
|
| IHC-Fr | (2) |
Use at an assay dependent concentration.
|
| IHC-FoFr | (1) |
Use at an assay dependent concentration.
|
| ICC/IF | (3) |
Use at an assay dependent concentration. PubMed: 20086251
|
| WB | (8) |
Use a concentration of 1 - 4 µg/ml. Can be blocked with Annexin V/ANXA5 peptide (ab52111).
|
| Flow Cyt | (1) |
Use at an assay dependent concentration.
ab171870 - Rabbit polyclonal IgG, is suitable for use as an isotype control with this antibody. |
| 特記事項 |
|---|
|
IHC-P
Use at an assay dependent concentration. |
|
IHC-Fr
Use at an assay dependent concentration. |
|
IHC-FoFr
Use at an assay dependent concentration. |
|
ICC/IF
Use at an assay dependent concentration. PubMed: 20086251 |
|
WB
Use a concentration of 1 - 4 µg/ml. Can be blocked with Annexin V/ANXA5 peptide (ab52111). |
|
Flow Cyt
Use at an assay dependent concentration. ab171870 - Rabbit polyclonal IgG, is suitable for use as an isotype control with this antibody. |
ターゲット情報
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機能
This protein is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade. -
関連疾患
Pregnancy loss, recurrent, 3 -
配列類似性
Belongs to the annexin family.
Contains 4 annexin repeats. -
ドメイン
The [IL]-x-C-x-x-[DE] motif is a proposed target motif for cysteine S-nitrosylation mediated by the iNOS-S100A8/A9 transnitrosylase complex.
A pair of annexin repeats may form one binding site for calcium and phospholipid. -
翻訳後修飾
S-nitrosylation is induced by interferon-gamma and oxidatively-modified low-densitity lipoprotein (LDL(ox)) possibly implicating the iNOS-S100A8/9 transnitrosylase complex. - Information by UniProt
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参照データベース
- Entrez Gene: 308 Human
- Entrez Gene: 11747 Mouse
- Entrez Gene: 25673 Rat
- Omim: 131230 Human
- SwissProt: P08758 Human
- SwissProt: P48036 Mouse
- SwissProt: P14668 Rat
- Unigene: 480653 Human
see all -
別名
- Anchorin CII antibody
- Annexin 5 antibody
- Annexin A5 antibody
see all
画像
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Western blot - Anti-Annexin V/ANXA5 antibody (ab14196)Anti-Annexin V/ANXA5 antibody (ab14196) + HeLa cell lysate
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (76)
ab14196 は 76 報の論文で使用されています。
- Marsilio S et al. Characterization of the intestinal mucosal proteome in cats with inflammatory bowel disease and alimentary small cell lymphoma. J Vet Intern Med 35:179-189 (2021). PubMed: 33471936
- Feige P et al. Analysis of human satellite cell dynamics on cultured adult skeletal muscle myofibers. Skelet Muscle 11:1 (2021). PubMed: 33397479
- Haeckel A et al. Long-circulating XTEN864-annexin A5 fusion protein for phosphatidylserine-related therapeutic applications. Apoptosis 26:534-547 (2021). PubMed: 34405304
- Kumar M et al. Defects in Mitochondrial Biogenesis Drive Mitochondrial Alterations in PARKIN-Deficient Human Dopamine Neurons. Stem Cell Reports 15:629-645 (2020). PubMed: 32795422
- Tian M et al. Adipose-Derived Biogenic Nanoparticles for Suppression of Inflammation. Small 16:e1904064 (2020). PubMed: 32067382