Anti-ALDH1L1 抗体 - Astrocyte Marker (ab190298)
Key features and details
- Rabbit polyclonal to ALDH1L1 - Astrocyte Marker
- Suitable for: WB, ICC/IF
- Reacts with: Rat, Human
- Isotype: IgG
製品の概要
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製品名
Anti-ALDH1L1 antibody - Astrocyte Marker
ALDH1L1 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to ALDH1L1 - Astrocyte Marker -
由来種
Rabbit -
アプリケーション
適用あり: WB, ICC/IFmore details -
種交差性
交差種: Rat, Human
交差が予測される動物種: Orangutan -
免疫原
Recombinant full length protein corresponding to Human ALDH1L1 aa 1 to the C-terminus. Immunogen expressed and purified from E. coli.
Database link: O75891 -
特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
バッファー
Preservative: 0.03% Sodium azide -
Concentration information loading...
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精製度
Whole antiserum -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab190298の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
---|---|---|
WB | (1) |
1/5000 - 1/10000. Predicted molecular weight: 99 kDa.
|
ICC/IF |
1/2000.
|
特記事項 |
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WB
1/5000 - 1/10000. Predicted molecular weight: 99 kDa. |
ICC/IF
1/2000. |
ターゲット情報
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組織特異性
Highly expressed in liver, pancreas and kidney. -
配列類似性
In the N-terminal section; belongs to the GART family.
In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily.
Contains 1 acyl carrier domain. -
細胞内局在
Cytoplasm. - Information by UniProt
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参照データベース
- Entrez Gene: 10840 Human
- Entrez Gene: 64392 Rat
- Omim: 600249 Human
- SwissProt: O75891 Human
- SwissProt: Q5RFM9 Orangutan
- SwissProt: P28037 Rat
- Unigene: 434435 Human
- Unigene: 2328 Rat
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別名
- 10 formyltetrahydrofolate dehydrogenase antibody
- 10 FTHFDH antibody
- 10-formyltetrahydrofolate dehydrogenase antibody
see all
画像
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Anti-ALDH1L1 antibody - Astrocyte Marker (ab190298) at 1/5000 dilution + Rat liver tissue homogenate
Predicted band size: 99 kDa
Observed band size: ~100 kDa why is the actual band size different from the predicted? -
Immunofluorescent analysis of human neuron-glial cell mixture cultures labeling ALDH1L1 with ab190298 at 1/2000 (red) and a monoclonal antibody against GFAP (green). Blue is a DNA stain. Astrocytes labeled by ab190298 and anti-GFAP appear yellow.
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (14)
ab190298 は 14 報の論文で使用されています。
- Falcone C et al. Redefining varicose projection astrocytes in primates. Glia 70:145-154 (2022). PubMed: 34533866
- Badia-Soteras A et al. High-Throughput Analysis of Astrocyte Cultures Shows Prevention of Reactive Astrogliosis by the Multi-Nutrient Combination Fortasyn Connect. Cells 11:N/A (2022). PubMed: 35563732
- Bassil R et al. Improved modeling of human AD with an automated culturing platform for iPSC neurons, astrocytes and microglia. Nat Commun 12:5220 (2021). PubMed: 34471104
- Padmashri R et al. Modeling human-specific interlaminar astrocytes in the mouse cerebral cortex. J Comp Neurol 529:802-810 (2021). PubMed: 32639590
- Etienne J et al. Aldehyde dehydrogenases contribute to skeletal muscle homeostasis in healthy, aging, and Duchenne muscular dystrophy patients. J Cachexia Sarcopenia Muscle 11:1047-1069 (2020). PubMed: 32157826