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ab81283 は 243 報の論文で使用されています。

  • Wu D  et al. MicroRNA-17 promotes osteosarcoma cells proliferation and migration and inhibits apoptosis by regulating SASH1 expression. Pathol Res Pract 215:115-120 (2019). PubMed: 30396754
  • Wang G  et al. Stimulation of tolerogenic dendritic cells using dexamethasone and 1,25-dihydroxyvitamin D3 represses autologous T cell activation and chondrocyte inflammation. Exp Ther Med 17:679-688 (2019). PubMed: 30651850
  • Yuan YH  et al. Epigenetic inactivation of HOXD10 is associated with human colon cancer via inhibiting the RHOC/AKT/MAPK signaling pathway. Cell Commun Signal 17:9 (2019). PubMed: 30683109
  • Wang L  et al. miR-122 and miR-199 synergistically promote autophagy in oral lichen planus by targeting the Akt/mTOR pathway. Int J Mol Med 43:1373-1381 (2019). PubMed: 30664152
  • He J  et al. BCL2L10/BECN1 modulates hepatoma cells autophagy by regulating PI3K/AKT signaling pathway. Aging (Albany NY) 11:350-370 (2019). PubMed: 30696802
  • Sun X  et al. Inhibition of NET-1 suppresses proliferation and promotes apoptosis of hepatocellular carcinoma cells by activating the PI3K/AKT signaling pathway. Exp Ther Med 17:2334-2340 (2019). PubMed: 30867719
  • Yuan T  et al. Inhibition of the PI3K/AKT signaling pathway sensitizes diffuse large B-cell lymphoma cells to treatment with proteasome inhibitors via suppression of BAG3. Oncol Lett 17:3719-3726 (2019). PubMed: 30881494
  • Wang X  et al. GPR 30 reduces myocardial infarct area and fibrosis in female ovariectomized mice by activating the PI3K/AKT pathway. Life Sci 226:22-32 (2019). PubMed: 30905784
  • Chen X  et al. Decoy receptor-3 regulates inflammation and apoptosis via PI3K/AKT signaling pathway in coronary heart disease. Exp Ther Med 17:2614-2622 (2019). PubMed: 30906453
  • Yang Z  et al. Baicalein improves glucose metabolism in insulin resistant HepG2 cells. Eur J Pharmacol 854:187-193 (2019). PubMed: 30970232
  • Imai T  et al. Rap1 signal modulators control the maintenance of hematopoietic progenitors in bone marrow and adult long-term hematopoiesis. Cancer Sci 110:1317-1330 (2019). PubMed: 30767320
  • Li D  et al. Mg-Zn-Mn alloy extract induces the angiogenesis of human umbilical vein endothelial cells via FGF/FGFR signaling pathway. Biochem Biophys Res Commun 514:618-624 (2019). PubMed: 31076107
  • Li Y  et al. Involvement of the PI3K/Akt/Nrf2 Signaling Pathway in Resveratrol-Mediated Reversal of Drug Resistance in HL-60/ADR Cells. Nutr Cancer 71:1007-1018 (2019). PubMed: 31032633
  • Zhang Y  et al. Ailanthone up-regulates miR-449a to restrain acute myeloid leukemia cells growth, migration and invasion. Exp Mol Pathol 108:114-120 (2019). PubMed: 31002772
  • Zhu J  et al. NKX2-8 deletion-induced reprogramming of fatty acid metabolism confers chemoresistance in epithelial ovarian cancer. EBioMedicine 43:238-252 (2019). PubMed: 31047858
  • Yu S  et al. Long noncoding RNA H19 promotes chemotherapy resistance in choriocarcinoma cells. J Cell Biochem N/A:N/A (2019). PubMed: 31020694
  • Guo C  et al. Spherical silica nanoparticles promote malignant transformation of BEAS-2B cells by stromal cell-derived factor-1a (SDF-1a). J Int Med Res 47:1264-1278 (2019). PubMed: 30727793
  • Durymanov M  et al. Subcutaneous Inoculation of 3D Pancreatic Cancer Spheroids Results in Development of Reproducible Stroma-Rich Tumors. Transl Oncol 12:180-189 (2019). PubMed: 30554606
  • Wang Y  et al. Mechanism of Regulation of Big-Conductance Ca2+-Activated K+ Channels by mTOR Complex 2 in Podocytes. Front Physiol 10:167 (2019). PubMed: 30873046
  • Wang M  et al. Protective effects of Myrica rubra flavonoids against hypoxia/reoxygenation-induced cardiomyocyte injury via the regulation of the PI3K/Akt/GSK3ß pathway. Int J Mol Med 43:2133-2143 (2019). PubMed: 30864694
  • Farzaneh Behelgardi M  et al. A peptide mimicking the binding sites of VEGF-A and VEGF-B inhibits VEGFR-1/-2 driven angiogenesis, tumor growth and metastasis. Sci Rep 8:17924 (2018). PubMed: 30560942
  • Zhu T  et al. LncRNA DUXAP9-206 directly binds with Cbl-b to augment EGFR signaling and promotes non-small cell lung cancer progression. J Cell Mol Med N/A:N/A (2018). PubMed: 30515972
  • Duan P  et al. Opening of mitoKATP improves cardiac function and inhibits apoptosis via the AKT-Foxo1 signaling pathway in diabetic cardiomyopathy. Int J Mol Med 42:2709-2719 (2018). PubMed: 30132505
  • Jiang W  et al. Wentilactone A induces cell apoptosis by targeting AKR1C1 gene via the IGF-1R/IRS1/PI3K/AKT/Nrf2/FLIP/Caspase-3 signaling pathway in small cell lung cancer. Oncol Lett 16:6445-6457 (2018). PubMed: 30405782
  • Maidarti M  et al. Inhibition of PTEN activates bovine non-growing follicles in vitro but increases DNA damage and reduces DNA repair response. Hum Reprod N/A:N/A (2018). PubMed: 30521029
  • Wang J  et al. Transcriptome Profiling Reveals PHLDA1 as a Novel Molecular Marker for Ischemic Cardiomyopathy. J Mol Neurosci N/A:N/A (2018). PubMed: 29736818
  • Jin X  et al. Overexpression of retinoblastoma-binding protein 4 contributes to the radiosensitivity of AGS gastric cancer cells via phosphoinositide3-kinase/protein kinase B pathway suppression. Mol Med Rep 18:1571-1581 (2018). PubMed: 29901205
  • Jin J  et al. miR-448 targets Rab2B and is pivotal in the suppression of pancreatic cancer. Oncol Rep 40:1379-1389 (2018). PubMed: 30015954
  • Zhu J  et al. Beclin1 overexpression suppresses tumor cell proliferation and survival via an autophagy-dependent pathway in human synovial sarcoma cells. Oncol Rep 40:1927-1936 (2018). PubMed: 30066884
  • Liang W  et al. Protective effects of rutin on liver injury in type 2 diabetic db/db mice. Biomed Pharmacother 107:721-728 (2018). PubMed: 30138894
  • Wudtiwai B  et al. Alpha-mangostin, an active compound in Garcinia mangostana, abrogates anoikis-resistance in human hepatocellular carcinoma cells. Toxicol In Vitro 53:222-232 (2018). PubMed: 30195041
  • Tian Y  et al. CXCL12 induces migration of oligodendrocyte precursor cells through the CXCR4-activated MEK/ERK and PI3K/AKT pathways. Mol Med Rep 18:4374-4380 (2018). PubMed: 30221695
  • Liu Y  et al. Ghrelin protects the myocardium with hypoxia/reoxygenation treatment through upregulating the expression of growth hormone, growth hormone secretagogue receptor and insulin-like growth factor-1, and promoting the phosphorylation of protein kinase B. Int J Mol Med 42:3037-3046 (2018). PubMed: 30272367
  • Yang F  et al. Sulforaphane induces autophagy by inhibition of HDAC6-mediated PTEN activation in triple negative breast cancer cells. Life Sci 213:149-157 (2018). PubMed: 30352240
  • Huang M  et al. Apatinib affect VEGF-mediated cell proliferation, migration, invasion via blocking VEGFR2/RAF/MEK/ERK and PI3K/AKT pathways in cholangiocarcinoma cell. BMC Gastroenterol 18:169 (2018). PubMed: 30400838
  • Ye L  et al. NUMB maintains bone mass by promoting degradation of PTEN and GLI1 via ubiquitination in osteoblasts. Bone Res 6:32 (2018). PubMed: 30455992
  • Liu H  et al. LncRNA XIST/miR-34a axis modulates the cell proliferation and tumor growth of thyroid cancer through MET-PI3K-AKT signaling. J Exp Clin Cancer Res 37:279 (2018). PubMed: 30463570
  • Xiang T  et al. Vasculogenic mimicry formation in EBV-associated epithelial malignancies. Nat Commun 9:5009 (2018). PubMed: 30479336
  • Jin YL  et al. Polydatin exerts anti-tumor effects against renal cell carcinoma cells via induction of caspase-dependent apoptosis and inhibition of the PI3K/Akt pathway. Onco Targets Ther 11:8185-8195 (2018). PubMed: 30532558
  • Liu Y & Zhang Y Lycium barbarum polysaccharides alleviate hydrogen peroxide-induced injury by up-regulation of miR-4295 in human trabecular meshwork cells. Exp Mol Pathol 106:109-115 (2018). PubMed: 30594603
  • Zeng Q  et al. Inhibition of REDD1 Sensitizes Bladder Urothelial Carcinoma to Paclitaxel by Inhibiting Autophagy. Clin Cancer Res 24:445-459 (2018). PubMed: 29084921
  • Zhou Z  et al. Apigenin suppresses the apoptosis of H9C2 rat cardiomyocytes subjected to myocardial ischemia-reperfusion injury via upregulation of the PI3K/Akt pathway. Mol Med Rep 18:1560-1570 (2018). PubMed: 29901074
  • Yang P  et al. miR-140-5p regulates cell migration and invasion of non-small cell lung cancer cells through targeting VEGFA. Mol Med Rep 18:2866-2872 (2018). PubMed: 30015904
  • Zhao W  et al. Transcription factor ATF3 mediates the radioresistance of breast cancer. J Cell Mol Med 22:4664-4675 (2018). PubMed: 30117642
  • Wang Z  et al. Association between AKT rs2494752 single nucleotide polymorphism and the risk of metastasis in hepatocellular carcinoma. Oncol Lett 16:3699-3705 (2018). PubMed: 30127980
  • Zhang Y  et al. Treatment with placental growth factor attenuates myocardial ischemia/reperfusion injury. PLoS One 13:e0202772 (2018). PubMed: 30212490
  • Hu N & Zhang H CYP24A1 depletion facilitates the antitumor effect of vitamin D3 on thyroid cancer cells. Exp Ther Med 16:2821-2830 (2018). PubMed: 30233662
  • Wang Y  et al. Guanidinoacetic Acid Regulates Myogenic Differentiation and Muscle Growth Through miR-133a-3p and miR-1a-3p Co-mediated Akt/mTOR/S6K Signaling Pathway. Int J Mol Sci 19:N/A (2018). PubMed: 30235878
  • Dai X  et al. Src kinase inhibitor PP2 regulates the biological characteristics of A549 cells via the PI3K/Akt signaling pathway. Oncol Lett 16:5059-5065 (2018). PubMed: 30250573
  • Zhang S  et al. Dorsal Root Ganglion Maintains Stemness of Bone Marrow Mesenchymal Stem Cells by Enhancing Autophagy through the AMPK/mTOR Pathway in a Coculture System. Stem Cells Int 2018:8478953 (2018). PubMed: 30363977
  • Lu Y  et al. Transcriptome Profiling of Neovascularized Corneas Reveals miR-204 as a Multi-target Biotherapy Deliverable by rAAVs. Mol Ther Nucleic Acids 10:349-360 (2018). WB . PubMed: 29499946
  • Jiang Y  et al. TIPE2 governs macrophage polarization via negative regulation of mTORC1. Mol Med Rep 17:952-960 (2018). PubMed: 29115630
  • Wang S & Gu K Insulin-like growth factor 1 inhibits autophagy of human colorectal carcinoma drug-resistant cells via the protein kinase B/mammalian target of rapamycin signaling pathway. Mol Med Rep 17:2952-2956 (2018). PubMed: 29257307
  • Ye K  et al. Ang1/Tie2 induces cell proliferation and migration in human papillary thyroid carcinoma via the PI3K/AKT pathway. Oncol Lett 15:1313-1318 (2018). PubMed: 29387247
  • Lin Y  et al. Effects of combined radiosurgery and temozolomide therapy on epidermal growth factor receptor and variant III in glioblastoma multiforme. Oncol Lett 15:5751-5759 (2018). PubMed: 29563997
  • Chen Y  et al. Testicular orphan receptor 4 promotes tumor progression and implies poor survival through AKT3 regulation in seminoma. Cancer Sci 109:384-394 (2018). PubMed: 29197138
  • Tankiewicz-Kwedlo A  et al. Simultaneous use of erythropoietin and LFM-A13 as a new therapeutic approach for colorectal cancer. Br J Pharmacol 175:743-762 (2018). IHC-P . PubMed: 29160911
  • He D  et al. Apolipoprotein A-1 mimetic peptide 4F promotes endothelial repairing and compromises reendothelialization impaired by oxidized HDL through SR-B1. Redox Biol 15:228-242 (2018). WB ; Mouse . PubMed: 29277016
  • Liu W  et al. Dioscin inhibits stem-cell-like properties and tumor growth of osteosarcoma through Akt/GSK3/ß-catenin signaling pathway. Cell Death Dis 9:343 (2018). PubMed: 29497056
  • Yang R  et al. Knockout of the placenta specific 8 gene radiosensitizes nasopharyngeal carcinoma cells by activating the PI3K/AKT/GSK3ß pathway. Am J Transl Res 10:455-464 (2018). PubMed: 29511439
  • Kovalchuk A  et al. Growth of Triple Negative and Progesterone Positive Breast Cancer Causes Oxidative Stress and Down-Regulates Neuroprotective Transcription Factor NPAS4 and NPAS4-Regulated Genes in Hippocampal Tissues of TumorGraft Mice-an Aging Connection. Front Genet 9:58 (2018). WB . PubMed: 29556248
  • Gu Y  et al. BCL6B suppresses proliferation and migration of colorectal carcinoma cells through inhibition of the PI3K/AKT signaling pathway. Int J Mol Med 41:2660-2668 (2018). PubMed: 29393377
  • Zhang B  et al. Metastasis-associated protein 2 promotes the metastasis of non-small cell lung carcinoma by regulating the ERK/AKT and VEGF signaling pathways. Mol Med Rep 17:4899-4908 (2018). PubMed: 29393472
  • Guo J  et al. Androgen receptor reverts dexamethasone-induced inhibition of prostate cancer cell proliferation and migration. Mol Med Rep 17:5887-5893 (2018). PubMed: 29436611
  • Yang XS  et al. Ouabain suppresses the growth and migration abilities of glioma U-87MG cells through inhibiting the Akt/mTOR signaling pathway and downregulating the expression of HIF-1a. Mol Med Rep 17:5595-5600 (2018). PubMed: 29436645
  • Liu S & Liu B Overexpression of Nitrogen Permease Regulator Like-2 (NPRL2) Enhances Sensitivity to Irinotecan (CPT-11) in Colon Cancer Cells by Activating the DNA Damage Checkpoint Pathway. Med Sci Monit 24:1424-1433 (2018). PubMed: 29519997
  • Luo J  et al. Elevated Expression of IRS-1 Associates with p-Akt Expression and Predicts Poor Prognosis of Breast Invasive Ductal Carcinoma. Hum Pathol N/A:N/A (2018). PubMed: 29551677
  • Zeng B  et al. SPP1 promotes ovarian cancer progression via Integrin ß1/FAK/AKT signaling pathway. Onco Targets Ther 11:1333-1343 (2018). PubMed: 29559792
  • Zhang J & Li Z ß-inducible gene-h3 promotes human breast carcinoma cell metastasis by activating the phosphatidylinositol 3-kinase/protein kinase B signaling pathway. Exp Ther Med 15:2910-2916 (2018). PubMed: 29599830
  • Li N  et al. Effects of isoliquiritigenin on ovarian cancer cells. Onco Targets Ther 11:1633-1642 (2018). PubMed: 29606882
  • Prabakaran AD  et al. Identification of early indicators of altered metabolism in normal development using a rodent model system. Dis Model Mech 11:N/A (2018). PubMed: 29434026
  • Wang L  et al. TIPE-2 suppresses growth and aggressiveness of hepatocellular carcinoma cells through downregulation of the phosphoinositide 3-kinase/AKT signaling pathway. Mol Med Rep 17:7017-7026 (2018). PubMed: 29568863
  • Oldrini B  et al. Somatic genome editing with the RCAS-TVA-CRISPR-Cas9 system for precision tumor modeling. Nat Commun 9:1466 (2018). PubMed: 29654229
  • Zhang Q  et al. PPAR? Antagonizes Hypoxia-Induced Activation of Hepatic Stellate Cell through Cross Mediating PI3K/AKT and cGMP/PKG Signaling. PPAR Res 2018:6970407 (2018). PubMed: 29686697
  • Hyrenius-Wittsten A  et al. De novo activating mutations drive clonal evolution and enhance clonal fitness in KMT2A-rearranged leukemia. Nat Commun 9:1770 (2018). PubMed: 29720585
  • Jia Z  et al. miR-126 suppresses epithelial-to-mesenchymal transition and metastasis by targeting PI3K/AKT/Snail signaling of lung cancer cells. Oncol Lett 15:7369-7375 (2018). PubMed: 29725450
  • Liu S  et al. Silencing Livin improved the sensitivity of colon cancer cells to 5-fluorouracil by regulating crosstalk between apoptosis and autophagy. Oncol Lett 15:7707-7715 (2018). PubMed: 29740490
  • Zhou S  et al. Low expression of SEMA6C accelerates the primordial follicle activation in the neonatal mouse ovary. J Cell Mol Med 22:486-496 (2018). WB ; Mouse . PubMed: 28881413
  • zur Nedden S  et al. Protein kinase N1 critically regulates cerebellar development and long-term function. J Clin Invest 128:2076-2088 (2018). PubMed: 29494346
  • Ma W  et al. Induction of chemokine (C-C motif) ligand 5 by Epstein-Barr virus infection enhances tumor angiogenesis in nasopharyngeal carcinoma. Cancer Sci 109:1710-1722 (2018). PubMed: 29569795
  • Ding Q  et al. Lack of endogenous parathyroid hormone delays fracture healing by inhibiting vascular endothelial growth factor-mediated angiogenesis. Int J Mol Med 42:171-181 (2018). PubMed: 29620150
  • Zhang Y  et al. PRL-3 promotes gastric cancer peritoneal metastasis via the PI3K/AKT signaling pathway in vitro and in vivo. Oncol Lett 15:9069-9074 (2018). PubMed: 29805638
  • Li J  et al. Down-regulation of microRNA-27b promotes retinal pigment epithelial cell proliferation and migration by targeting Nox2. Pathol Res Pract 214:925-933 (2018). WB ; Human . PubMed: 29858119
  • Cao Y  et al. DA5-CH, a novel GLP-1/GIP dual agonist, effectively ameliorates the cognitive impairments and pathology in the APP/PS1 mouse model of Alzheimer's disease. Eur J Pharmacol 827:215-226 (2018). Mouse . PubMed: 29551659
  • Cui Y & Yang S Overexpression of Annexin A1 protects against benzo[a]pyrene-induced bronchial epithelium injury. Mol Med Rep 18:349-357 (2018). PubMed: 29749523
  • Li L  et al. TRIM22 knockdown suppresses chronic myeloid leukemia via inhibiting PI3K/Akt/mTOR signaling pathway. Cell Biol Int N/A:N/A (2018). PubMed: 29762880
  • Zheng Y  et al. Pinocembrin induces ER stress mediated apoptosis and suppresses autophagy in melanoma cells. Cancer Lett 431:31-42 (2018). PubMed: 29807112
  • Sun J  et al. XK-related protein 5 (XKR5) is a novel negative regulator of KIT/D816V-mediated transformation. Oncogenesis 7:48 (2018). PubMed: 29910466
  • Liu F  et al. Prolonged inhibition of class I PI3K promotes liver cancer stem cell expansion by augmenting SGK3/GSK-3ß/ß-catenin signalling. J Exp Clin Cancer Res 37:122 (2018). PubMed: 29940988
  • Pan LY  et al. Mechanism of Yanghe Pingchuan granules treatment for airway remodeling in asthma. Drug Des Devel Ther 12:1941-1951 (2018). PubMed: 29983548
  • Xu H  et al. SIL1 functions as an oncogene in glioma by AKT/mTOR signaling pathway. Onco Targets Ther 11:3775-3783 (2018). PubMed: 29997438
  • Chen W  et al. Downregulation of lncRNA OGFRP1 inhibits hepatocellular carcinoma progression by AKT/mTOR and Wnt/ß-catenin signaling pathways. Cancer Manag Res 10:1817-1826 (2018). PubMed: 29997441
  • Wang Y  et al. Sirt3-mediated mitochondrial fission regulates the colorectal cancer stress response by modulating the Akt/PTEN signalling pathway. Biomed Pharmacother 105:1172-1182 (2018). PubMed: 30021354
  • Rasheduzzaman M  et al. Resveratrol sensitizes lung cancer cell to TRAIL by p53 independent and suppression of Akt/NF-?B signaling. Life Sci 208:208-220 (2018). PubMed: 30031063
  • Kamerkar S  et al. Exosomes facilitate therapeutic targeting of oncogenic KRAS in pancreatic cancer. Nature 546:498-503 (2017). IHC-P ; Human . PubMed: 28607485
  • Zhang B  et al. Bitterness in sugar: O-GlcNAcylation aggravates pre-B acute lymphocytic leukemia through glycolysis via the PI3K/Akt/c-Myc pathway. Am J Cancer Res 7:1337-1349 (2017). WB ; Human . PubMed: 28670495
  • Wu CE  et al. Comparative global immune-related gene profiling of somatic cells, human pluripotent stem cells and their derivatives: implication for human lymphocyte proliferation. Exp Mol Med 49:e376 (2017). WB . PubMed: 28912571
  • Liang Z  et al. MicroRNA-608 inhibits proliferation of bladder cancer via AKT/FOXO3a signaling pathway. Mol Cancer 16:96 (2017). WB ; Human . PubMed: 28549468
  • Yuan H  et al. FGF2/FGFR1 regulates autophagy in FGFR1-amplified non-small cell lung cancer cells. J Exp Clin Cancer Res 36:72 (2017). PubMed: 28558758
  • Jin X  et al. HO-1/EBP interaction alleviates cholesterol-induced hypoxia through the activation of the AKT and Nrf2/mTOR pathways and inhibition of carbohydrate metabolism in cardiomyocytes. Int J Mol Med 39:1409-1420 (2017). PubMed: 28487965
  • Zhou W  et al. MicroRNA-138 inhibits hypoxia-induced proliferation of endothelial progenitor cells via inhibition of HIF-1a-mediated MAPK and AKT signaling. Exp Ther Med 13:1017-1024 (2017). WB ; Human . PubMed: 28450935
  • Yang L  et al. Total Flavonoids Extracted from Oxytropis falcata Bunge Improve Insulin Resistance through Regulation on the IKKß/NF-?B Inflammatory Pathway. Evid Based Complement Alternat Med 2017:2405124 (2017). WB ; Rat . PubMed: 28458712
  • Majumder P  et al. Cellular levels of Grb2 and cytoskeleton stability are correlated in a neurodegenerative scenario. Dis Model Mech 10:655-669 (2017). PubMed: 28360125
  • El Gamal H  et al. Renoprotective Effects of Aldose Reductase Inhibitor Epalrestat against High Glucose-Induced Cellular Injury. Biomed Res Int 2017:5903105 (2017). WB . PubMed: 28386557
  • Jiang G  et al. Mediation of insulin growth factor-1 in Alzheimer's disease and the mechanism of PRNP genetic expression and the PI3K/Akt signaling pathway. Exp Ther Med 13:2763-2766 (2017). WB . PubMed: 28587338
  • Su W  et al. GABARAPL1 suppresses metastasis by counteracting PI3K/Akt pathway in prostate cancer. Oncotarget 8:4449-4459 (2017). PubMed: 27966458
  • Chen J  et al. AIM2 regulates viability and apoptosis in human colorectal cancer cells via the PI3K/Akt pathway. Onco Targets Ther 10:811-817 (2017). WB . PubMed: 28243117
  • Chen Y  et al. Proliferation and invasion of ovarian cancer cells are suppressed by knockdown of TRIM11. Oncol Lett 14:2125-2130 (2017). PubMed: 28781653
  • Chen X  et al. The role of sodium hydrosulfide in attenuating the aging process via PI3K/AKT and CaMKKß/AMPK pathways. Redox Biol 12:987-1003 (2017). PubMed: 28499253
  • Chen S  et al. Long non-coding RNA PTENP1 inhibits proliferation and migration of breast cancer cells via AKT and MAPK signaling pathways. Oncol Lett 14:4659-4662 (2017). WB ; Human . PubMed: 29085464
  • Kazi JU  et al. ABL2 suppresses FLT3-ITD-induced cell proliferation through negative regulation of AKT signaling. Oncotarget 8:12194-12202 (2017). Mouse . PubMed: 28086240
  • Cao Y  et al. Ginsenoside Rg3 inhibits angiogenesis in a rat model of endometriosis through the VEGFR-2-mediated PI3K/Akt/mTOR signaling pathway. PLoS One 12:e0186520 (2017). PubMed: 29140979
  • Moharram SA  et al. T-cell Acute Lymphoblastic Leukemia Cells Display Activation of Different Survival Pathways. J Cancer 8:4124 (2017). PubMed: 29187889
  • Su WJ  et al. Antidiabetic drug glyburide modulates depressive-like behavior comorbid with insulin resistance. J Neuroinflammation 14:210 (2017). PubMed: 29084550
  • Yu W  et al. A nomogram based on phosphorylated AKT1 for predicting locoregional recurrence in patients with oesophageal squamous cell carcinoma. J Cancer 8:3755-3763 (2017). IHC-P ; Human . PubMed: 29151963
  • Rai SN  et al. Mucuna pruriens Protects against MPTP Intoxicated Neuroinflammation in Parkinson's Disease through NF-?B/pAKT Signaling Pathways. Front Aging Neurosci 9:421 (2017). PubMed: 29311905
  • Feng F  et al. Hoxa5 increases mitochondrial apoptosis by inhibiting Akt/mTORC1/S6K1 pathway in mice white adipocytes. Oncotarget 8:95332-95345 (2017). PubMed: 29221131
  • Shuang W  et al. Mcl-1 stabilization confers resistance to taxol in human gastric cancer. Oncotarget 8:82981-82990 (2017). PubMed: 29137317
  • Qian LQ  et al. Downregulation of MACC1 inhibits the viability, invasion and migration and induces apoptosis in esophageal carcinoma cells through the phosphatase and tensin homolog/phosphoinositide 3-kinase/protein kinase B signaling pathway. Oncol Lett 14:4897-4905 (2017). PubMed: 29085498
  • Zeng X  et al. Acylated and unacylated ghrelin inhibit atrophy in myotubes co-cultured with colon carcinoma cells. Oncotarget 8:72872-72885 (2017). PubMed: 29069832
  • Shinsuke K  et al. Chronic irradiation with low-dose-rate 137Cs-? rays inhibits NGF-induced neurite extension of PC12 cells via Ca2+/calmodulin-dependent kinase II activation. J Radiat Res 58:809-815 (2017). PubMed: 29106600
  • Ke K & Lou T MicroRNA-10a suppresses breast cancer progression via PI3K/Akt/mTOR pathway. Oncol Lett 14:5994-6000 (2017). PubMed: 29113237
  • Diao S  et al. Trefoil factor 3 contributes to the malignancy of glioma via regulating HIF-1a. Oncotarget 8:76770-76782 (2017). PubMed: 29100347
  • Chen X  et al. Hydrogen Sulphide Treatment Increases Insulin Sensitivity and Improves Oxidant Metabolism through the CaMKKbeta-AMPK Pathway in PA-Induced IR C2C12 Cells. Sci Rep 7:13248 (2017). PubMed: 29038536
  • Liu Y  et al. The lipid metabolism gene FTO influences breast cancer cell energy metabolism via the PI3K/AKT signaling pathway. Oncol Lett 13:4685-4690 (2017). PubMed: 28599470
  • Ding P  et al. CD147 functions as the signaling receptor for extracellular divalent copper in hepatocellular carcinoma cells. Oncotarget 8:51151-51163 (2017). PubMed: 28881637
  • Zhang Y  et al. AGO2 involves the malignant phenotypes and FAK/PI3K/AKT signaling pathway in hypopharyngeal-derived FaDu cells. Oncotarget 8:54735-54746 (2017). PubMed: 28903378
  • Yang L  et al. The role of mTOR signaling pathway on cognitive functions in cerebral ischemia-reperfusion. Exp Ther Med 14:2839-2844 (2017). PubMed: 28912846
  • Si F  et al. MicroRNA-138 suppresses cell proliferation in laryngeal squamous cell carcinoma via inhibiting EZH2 and PI3K/AKT signaling. Exp Ther Med 14:1967-1974 (2017). PubMed: 28962111
  • Liang Z  et al. SUMOylation of IQGAP1 promotes the development of colorectal cancer. Cancer Lett 411:90-99 (2017). PubMed: 28987385
  • Fang JF  et al. Upregulation of RASAL2 promotes proliferation and metastasis, and is targeted by miR-203 in hepatocellular carcinoma. Mol Med Rep 15:2720-2726 (2017). PubMed: 28447723
  • Liu L  et al. HMGA1 participates in MHCC97H cell proliferation and invasion through the ILK/Akt/GSK3ß signaling pathway. Mol Med Rep 16:9287-9294 (2017). PubMed: 29152644
  • Yang CY  et al. Melatonin exerts anti-oral cancer effect via suppressing LSD1 in patient-derived tumor xenograft models. Oncotarget 8:33756-33769 (2017). WB . PubMed: 28422711
  • Prakoura N  et al. NF?B-Induced Periostin Activates Integrin-ß3 Signaling to Promote Renal Injury in GN. J Am Soc Nephrol 28:1475-1490 (2017). PubMed: 27920156
  • Liu W  et al. A new facet of NDRG1 in pancreatic ductal adenocarcinoma: Suppression of glycolytic metabolism. Int J Oncol 50:1792-1800 (2017). PubMed: 28350132
  • Yang HH  et al. Protective Effects of MicroRNA-126 on Human Cardiac Microvascular Endothelial Cells Against Hypoxia/Reoxygenation-Induced Injury and Inflammatory Response by Activating PI3K/Akt/eNOS Signaling Pathway. Cell Physiol Biochem 42:506-518 (2017). PubMed: 28578351
  • Xiao Q  et al. Mild hypothermia pretreatment protects against liver ischemia reperfusion injury via the PI3K/AKT/FOXO3a pathway. Mol Med Rep 16:7520-7526 (2017). PubMed: 28944825
  • Yuan D  et al. Effect of integrin-linked kinase gene silencing on microRNA expression in ovarian cancer. Mol Med Rep 16:7267-7276 (2017). PubMed: 28944870
  • Bian H  et al. Beneficial effects of extracts from Lucilia sericata maggots on burn wounds in rats. Mol Med Rep 16:7213-7220 (2017). PubMed: 28944889
  • Belkaid A  et al. 17ß-estradiol-induced ACSL4 protein expression promotes an invasive phenotype in estrogen receptor positive mammary carcinoma cells. Carcinogenesis 38:402-410 (2017). PubMed: 28334272
  • Peng HB  et al. Protective effects of oleanolic acid on oxidative stress and the expression of cytokines and collagen by the AKT/NF-?B pathway in silicotic rats. Mol Med Rep 15:3121-3128 (2017). PubMed: 28350071
  • Zhang J  et al. Zinc oxide nanoparticles harness autophagy to induce cell death in lung epithelial cells. Cell Death Dis 8:e2954 (2017). PubMed: 28749469
  • Jin X  et al. HO-1 alleviates cholesterol-induced oxidative stress through activation of Nrf2/ERK and inhibition of PI3K/AKT pathways in endothelial cells. Mol Med Rep 16:3519-3527 (2017). PubMed: 28713890
  • Guo YY  et al. Augmenter of liver regeneration potentiates doxorubicin anticancer efficacy by reducing the expression of ABCB1 and ABCG2 in hepatocellular carcinoma. Lab Invest 97:1400-1411 (2017). PubMed: 28825695
  • Lv L & Liu B Anti-tumor effects of bakuchiol on human gastric carcinoma cell lines are mediated through PI3K/AKT and MAPK signaling pathways. Mol Med Rep 16:8977-8982 (2017). PubMed: 28990045
  • Li HB  et al. Long Non-Coding RNA-MALAT1 Mediates Retinal Ganglion Cell Apoptosis Through the PI3K/Akt Signaling Pathway in Rats with Glaucoma. Cell Physiol Biochem 43:2117-2132 (2017). PubMed: 29065394
  • Fu J  et al. 1, 6-di-O-caffeoyl-ß-D-glucopyranoside, a natural compound from Callicarpa nudiflora Hook impairs P2Y12 and thromboxane A2 receptor-mediated amplification of platelet activation and aggregation. Phytomedicine 36:273-282 (2017). PubMed: 29157825
  • Jafari N  et al. p70S6K1 (S6K1)-mediated Phosphorylation Regulates Phosphatidylinositol 4-Phosphate 5-Kinase Type I ? Degradation and Cell Invasion. J Biol Chem 291:25729-25741 (2016). PubMed: 27780861
  • Hedl M  et al. IRF5 and IRF5 Disease-Risk Variants Increase Glycolysis and Human M1 Macrophage Polarization by Regulating Proximal Signaling and Akt2 Activation. Cell Rep 16:2442-55 (2016). PubMed: 27545875
  • Chen Y  et al. Discovery of benzenesulfonamide derivatives as potent PI3K/mTOR dual inhibitors with in vivo efficacies against hepatocellular carcinoma. Bioorg Med Chem 24:957-66 (2016). WB ; Human . PubMed: 26819001
  • Kong X  et al. MiR-155 promotes epithelial-mesenchymal transition in hepatocellular carcinoma cells through the activation of PI3K/SGK3/ß-catenin signaling pathways. Oncotarget 7:66051-66060 (2016). PubMed: 27602769
  • Wang Y  et al. Intrinsic cellular signaling mechanisms determine the sensitivity of cancer cells to virus-induced apoptosis. Sci Rep 6:37213 (2016). PubMed: 27849011
  • Boudra R  et al. mTOR transcriptionally and post-transcriptionally regulates Npm1 gene expression to contribute to enhanced proliferation in cells with Pten inactivation. Cell Cycle 15:1352-62 (2016). PubMed: 27050906
  • Xu J  et al. HER2 overexpression reverses the relative resistance of EGFR-mutant H1975 cell line to gefitinib. Oncol Lett 12:5363-5369 (2016). WB ; Human . PubMed: 28105244
  • Marcusso Orsini T  et al. Antileishmanial Activity and Inducible Nitric Oxide Synthase Activation by RuNO Complex. Mediators Inflamm 2016:2631625 (2016). ICC ; Mouse . PubMed: 27795620
  • Chen Y  et al. FGFR antagonist induces protective autophagy in FGFR1-amplified breast cancer cell. Biochem Biophys Res Commun N/A:N/A (2016). WB ; Human . PubMed: 26993162
  • Liang D  et al. Therapeutic efficacy of apelin on transplanted mesenchymal stem cells in hindlimb ischemic mice via regulation of autophagy. Sci Rep 6:21914 (2016). WB ; Mouse . PubMed: 26902855
  • Ma J  et al. microRNA-22 attenuates neuronal cell apoptosis in a cell model of traumatic brain injury. Am J Transl Res 8:1895-902 (2016). WB ; Rat . PubMed: 27186313
  • Khanom R  et al. Keratin 17 Is Induced in Oral Cancer and Facilitates Tumor Growth. PLoS One 11:e0161163 (2016). PubMed: 27512993
  • Lu Y  et al. HER2-siRNA delivered by EGFR-specific single chain antibody inhibits NSCLC cell proliferation and tumor growth. Oncotarget 7:23594-607 (2016). WB ; Human . PubMed: 26988752
  • Sajan M  et al. Brain Insulin Signaling Is Increased in Insulin-Resistant States and Decreases in FOXOs and PGC-1a and Increases in Aß1-40/42 and Phospho-Tau May Abet Alzheimer Development. Diabetes 65:1892-903 (2016). PubMed: 26895791
  • Chen YC  et al. High mobility group box 1-induced epithelial mesenchymal transition in human airway epithelial cells. Sci Rep 6:18815 (2016). WB ; Human . PubMed: 26739898
  • Han J  et al. Structure-based optimization leads to the discovery of NSC765844, a highly potent, less toxic and orally efficacious dual PI3K/mTOR inhibitor. Eur J Med Chem 122:684-701 (2016). WB ; Human . PubMed: 27448924
  • Lv P  et al. Treatment with the herbal medicine, naoxintong improves the protective effect of high-density lipoproteins on endothelial function in patients with type 2 diabetes. Mol Med Rep 13:2007-16 (2016). WB ; Human . PubMed: 26781332
  • Yang J  et al. PREX2 promotes the proliferation, invasion and migration of pancreatic cancer cells by modulating the PI3K signaling pathway. Oncol Lett 12:1139-1143 (2016). WB ; Human . PubMed: 27446408
  • He S  et al. Upregulation of PREX2 promotes the proliferation and migration of hepatocellular carcinoma cells via PTEN-AKT signaling. Oncol Lett 11:2223-2228 (2016). Human . PubMed: 26998152
  • Hou S  et al. Neuroprotective Effect of Salvianolic Acids against Cerebral Ischemia/Reperfusion Injury. Int J Mol Sci 17:N/A (2016). WB ; Rat . PubMed: 27455249
  • Guo W  et al. miR-200a regulates Rheb-mediated amelioration of insulin resistance after duodenal-jejunal bypass. Int J Obes (Lond) 40:1222-32 (2016). PubMed: 27121251
  • Liang Q  et al. Application of citrate as a tricarboxylic acid (TCA) cycle intermediate, prevents diabetic-induced heart damages in mice. Iran J Basic Med Sci 19:43-8 (2016). WB ; Mouse . PubMed: 27096063
  • Chen Q  et al. SPOCK1 promotes tumor growth and metastasis in human prostate cancer. Drug Des Devel Ther 10:2311-21 (2016). PubMed: 27486308
  • Liu Z  et al. Adiponectin reduces ER stress-induced apoptosis through PPARa transcriptional regulation of ATF2 in mouse adipose. Cell Death Dis 7:e2487 (2016). WB ; Mouse . PubMed: 27882945
  • Chen B  et al. STC2 promotes the epithelial-mesenchymal transition of colorectal cancer cells through AKT-ERK signaling pathways. Oncotarget 7:71400-71416 (2016). WB ; Human . PubMed: 27662663
  • Shen C  et al. Potential protective effects of autophagy activated in MPP+ treated astrocytes. Exp Ther Med 12:2803-2810 (2016). WB ; Mouse . PubMed: 27882077
  • Zhu Z  et al. Phosphorylated AKT1 is associated with poor prognosis in esophageal squamous cell carcinoma. J Exp Clin Cancer Res 34:95 (2015). IHC-P ; Human . PubMed: 26338103
  • Bauer J  et al. Activin and TGFß use diverging mitogenic signaling in advanced colon cancer. Mol Cancer 14:182 (2015). IHC-P ; Human . PubMed: 26497569
  • Wang C  et al. Clusterin facilitates metastasis by EIF3I/Akt/MMP13 signaling in hepatocellular carcinoma. Oncotarget 6:2903-16 (2015). IHC-P ; Human . PubMed: 25609201
  • Martínez-Fernández M  et al. Analysis of the Polycomb-related lncRNAs HOTAIR and ANRIL in bladder cancer. Clin Epigenetics 7:109 (2015). WB ; Human . PubMed: 26457124
  • Wu B  et al. Basigin-mediated redistribution of CD98 promotes cell spreading and tumorigenicity in hepatocellular carcinoma. J Exp Clin Cancer Res 34:110 (2015). Human . PubMed: 26437640
  • Han X  et al. CRISPR-Cas9 delivery to hard-to-transfect cells via membrane deformation. Sci Adv 1:e1500454 (2015). ICC/IF ; Human . PubMed: 26601238
  • Xu S  et al. Downregulation of long noncoding RNA MALAT1 induces epithelial-to-mesenchymal transition via the PI3K-AKT pathway in breast cancer. Int J Clin Exp Pathol 8:4881-91 (2015). WB ; Human . PubMed: 26191181
  • Liu SH  et al. Low-Concentration Arsenic Trioxide Inhibits Skeletal Myoblast Cell Proliferation via a Reactive Oxygen Species-Independent Pathway. PLoS One 10:e0137907 (2015). WB ; Mouse . PubMed: 26359868
  • Jung Y  et al. Annexin 2-CXCL12 interactions regulate metastatic cell targeting and growth in the bone marrow. Mol Cancer Res 13:197-207 (2015). ICC/IF ; Human . PubMed: 25139998
  • Zhang X  et al. PI3K/Akt/p53 pathway inhibits reovirus infection. Infect Genet Evol 34:415-22 (2015). PubMed: 26066464
  • Zhang J  et al. Comparisons of ethanol extracts of chinese propolis (poplar type) and poplar gums based on the antioxidant activities and molecular mechanism. Evid Based Complement Alternat Med 2015:307594 (2015). Mouse . PubMed: 25802536
  • Kariya Y  et al. Increased cerebrospinal fluid osteopontin levels and its involvement in macrophage infiltration in neuromyelitis optica. BBA Clin 3:126-34 (2015). Human . PubMed: 26673877
  • Shi Z  et al. Cables1 controls p21/Cip1 protein stability by antagonizing proteasome subunit alpha type 3. Oncogene 34:2538-45 (2015). PubMed: 24975575
  • Fan X  et al. A novel therapeutic strategy to rescue the immune effector function of proteolytically inactivated cancer therapeutic antibodies. Mol Cancer Ther 14:681-91 (2015). PubMed: 25552368
  • Bian Y  et al. Elevated Rictor expression is associated with tumor progression and poor prognosis in patients with gastric cancer. Biochem Biophys Res Commun 464:534-40 (2015). IHC-P ; Human . PubMed: 26159923
  • Xie J  et al. Calcium-sensing receptor is involved in the pathogenesis of fat emulsion-induced insulin resistance in rats. Mol Med Rep 12:2043-8 (2015). PubMed: 25892159
  • Zhao J  et al. Sp1-CD147 positive feedback loop promotes the invasion ability of ovarian cancer. Oncol Rep 34:67-76 (2015). PubMed: 25998266
  • Liu CJ  et al. MiR-214 promotes osteosarcoma tumor growth and metastasis by decreasing the expression of PTEN. Mol Med Rep 12:6261-6 (2015). PubMed: 26252022
  • Peng LX  et al. Phosphoinositide 3-kinase/Akt pathway is involved in pingyangmycin-induced growth inhibition, apoptosis and reduction of invasive potential in EOMA mouse hemangioendothelioma cells. Mol Med Rep 12:8275-81 (2015). PubMed: 26498320
  • Huang W  et al. Inhibition of KIF14 Suppresses Tumor Cell Growth and Promotes Apoptosis in Human Glioblastoma. Cell Physiol Biochem 37:1659-70 (2015). PubMed: 26536004
  • Zhang Z  et al. Upregulated periostin promotes angiogenesis in keloids through activation of the ERK 1/2 and focal adhesion kinase pathways, as well as the upregulated expression of VEGF and angiopoietin-1. Mol Med Rep 11:857-64 (2015). WB ; Human . PubMed: 25369801
  • Cekanaviciute E  et al. Astrocytic transforming growth factor-beta signaling reduces subacute neuroinflammation after stroke in mice. Glia 62:1227-40 (2014). PubMed: 24733756
  • Wang JF  et al. The molecular mechanisms of Tanshinone IIA on the apoptosis and arrest of human esophageal carcinoma cells. Biomed Res Int 2014:582730 (2014). WB ; Human . PubMed: 24829906
  • Liu R  et al. Itraconazole suppresses the growth of glioblastoma through induction of autophagy: involvement of abnormal cholesterol trafficking. Autophagy 10:1241-55 (2014). PubMed: 24905460
  • Chu HC  et al. Erythroid differentiation is augmented in Reelin-deficient K562 cells and homozygous reeler mice. FEBS Lett 588:58-64 (2014). PubMed: 24239537
  • Duan Y  et al. Effects of tonic immobility (TI) and corticosterone (CORT) on energy status and protein metabolism in pectoralis major muscle of broiler chickens. Comp Biochem Physiol A Mol Integr Physiol 169:90-5 (2014). Chicken . PubMed: 24389091
  • Guo W  et al. Targeting GRP75 improves HSP90 inhibitor efficacy by enhancing p53-mediated apoptosis in hepatocellular carcinoma. PLoS One 9:e85766 (2014). WB ; Human . PubMed: 24465691
  • Cui W  et al. Frequent copy number variations of PI3K/AKT pathway and aberrant protein expressions of PI3K subunits are associated with inferior survival in diffuse large B cell lymphoma. J Transl Med 12:10 (2014). IHC-P ; Human . PubMed: 24418330
  • Chiu CY  et al. Low-dose benzo(a)pyrene and its epoxide metabolite inhibit myogenic differentiation in human skeletal muscle-derived progenitor cells. Toxicol Sci 138:344-53 (2014). Human . PubMed: 24431215
  • Zhu HY  et al. MicroRNA-21 regulates hTERT via PTEN in hypertrophic scar fibroblasts. PLoS One 9:e97114 (2014). WB ; Human . PubMed: 24817011
  • Loubeau G  et al. NPM1 Silencing Reduces Tumour Growth and MAPK Signalling in Prostate Cancer Cells. PLoS One 9:e96293 (2014). WB . PubMed: 24796332
  • Hung CY  et al. Nucleolin enhances internal ribosomal entry site (IRES)-mediated translation of Sp1 in tumorigenesis. Biochim Biophys Acta 1843:2843-2854 (2014). PubMed: 25173817
  • Xu R  et al. The protease Omi regulates mitochondrial biogenesis through the GSK3ß/PGC-1a pathway. Cell Death Dis 5:e1373 (2014). WB ; Mouse . PubMed: 25118933
  • Sakaguchi M  et al. DNAX-activating protein 10 (DAP10) membrane adaptor associates with receptor for advanced glycation end products (RAGE) and modulates the RAGE-triggered signaling pathway in human keratinocytes. J Biol Chem 289:23389-402 (2014). PubMed: 25002577
  • de Joussineau C  et al. mTOR pathway is activated by PKA in adrenocortical cells and participates in vivo to apoptosis resistance in primary pigmented nodular adrenocortical disease (PPNAD). Hum Mol Genet 23:5418-28 (2014). PubMed: 24865460
  • Li J  et al. miR-200c overexpression is associated with better efficacy of EGFR-TKIs in non-small cell lung cancer patients with EGFR wild-type. Oncotarget 5:7902-16 (2014). WB ; Human . PubMed: 25277203
  • Gao Y  et al. Hypoxia induces cardiac fibroblast proliferation and phenotypic switch: a role for caveolae and caveolin-1/PTEN mediated pathway. J Thorac Dis 6:1458-68 (2014). WB ; Mouse . PubMed: 25364523
  • Santos M  et al. In vivo disruption of an Rb-E2F-Ezh2 signaling loop causes bladder cancer. Cancer Res 74:6565-77 (2014). PubMed: 25252918
  • Zhang J  et al. SOX4 inhibits GBM cell growth and induces G0/G1 cell cycle arrest through Akt-p53 axis. BMC Neurol 14:207 (2014). WB ; Human . PubMed: 25366337
  • Fu X  et al. Overcoming endocrine resistance due to reduced PTEN levels in estrogen receptor-positive breast cancer by co-targeting mammalian target of rapamycin, protein kinase B, or mitogen-activated protein kinase kinase. Breast Cancer Res 16:430 (2014). PubMed: 25212826
  • Chai S  et al. Ca(2+)/calmodulin-dependent protein kinase II?, a critical mediator of the NF-?B network, is a novel therapeutic target in non-small cell lung cancer. Cancer Lett N/A:N/A (2013). Human . PubMed: 24189456
  • Hu W  et al. AEBP1 upregulation confers acquired resistance to BRAF (V600E) inhibition in melanoma. Cell Death Dis 4:e914 (2013). WB ; Human . PubMed: 24201813
  • Liu CC  et al. The membrane-proximal KXGFFKR motif of a-integrin mediates chemoresistance. Mol Cell Biol 33:4334-45 (2013). WB ; Human . PubMed: 24001772
  • Iacovides DC  et al. Identification and quantification of AKT isoforms and phosphoforms in breast cancer using a novel nanofluidic immunoassay. Mol Cell Proteomics 12:3210-20 (2013). PubMed: 23929892
  • Wang KL  et al. Inhibitory effects of isoliquiritigenin on the migration and invasion of human breast cancer cells. Expert Opin Ther Targets 17:337-49 (2013). Human . PubMed: 23327692
  • Li R  et al. Imbalanced network biomarkers for traditional Chinese medicine Syndrome in gastritis patients. Sci Rep 3:1543 (2013). IHC-P ; Human . PubMed: 23529020
  • Kraus M  et al. Nelfinavir augments proteasome inhibition by bortezomib in myeloma cells and overcomes bortezomib and carfilzomib resistance. Blood Cancer J 3:e103 (2013). WB ; Human . PubMed: 23454896
  • Li Y  et al. Protein phosphatase 2A and DNA-dependent protein kinase are involved in mediating rapamycin-induced Akt phosphorylation. J Biol Chem 288:13215-24 (2013). IHC-P ; Human . PubMed: 23536185
  • Huang X  et al. XIAP inhibits autophagy via XIAP-Mdm2-p53 signalling. EMBO J 32:2204-16 (2013). Human . PubMed: 23749209
  • Chung CH  et al. Butein Inhibits Angiogenesis of Human Endothelial Progenitor Cells via the Translation Dependent Signaling Pathway. Evid Based Complement Alternat Med 2013:943187 (2013). WB ; Rat . PubMed: 23840271
  • Phung B  et al. Differential activity of c-KIT splice forms is controlled by extracellular peptide insert length. Cell Signal 25:2231-8 (2013). PubMed: 23880320
  • Yang M  et al. Saturated fatty acid palmitate-induced insulin resistance is accompanied with myotube loss and the impaired expression of health benefit myokine genes in C2C12 myotubes. Lipids Health Dis 12:104 (2013). WB ; Mouse . PubMed: 23866690
  • Xu MY  et al. Akebia saponin PA induces autophagic and apoptotic cell death in AGS human gastric cancer cells. Food Chem Toxicol 59:703-8 (2013). Human . PubMed: 23850994
  • Chuang JH  et al. Differentiation of glutamatergic neurons from mouse embryonic stem cells requires raptor S6K signaling. Stem Cell Res 11:1117-1128 (2013). Mouse . PubMed: 23988668
  • Hu FY  et al. AGGF1 is a novel anti-inflammatory factor associated with TNF-a-induced endothelial activation. Cell Signal 25:1645-53 (2013). PubMed: 23628701
  • Chang LH  et al. Activated PAR-2 regulates pancreatic cancer progression through ILK/HIF-a-induced TGF-a expression and MEK/VEGF-A-mediated angiogenesis. Am J Pathol 183:566-75 (2013). Human . PubMed: 23764046
  • Lin YH  et al. Thyroid hormone receptor represses miR-17 expression to enhance tumor metastasis in human hepatoma cells. Oncogene 32:4509-18 (2013). Human . PubMed: 23912452
  • Jin H  et al. Matrine activates PTEN to induce growth inhibition and apoptosis in V600EBRAF harboring melanoma cells. Int J Mol Sci 14:16040-57 (2013). WB ; Human . PubMed: 23912239
  • Cai J  et al. miR-205 targets PTEN and PHLPP2 to augment AKT signaling and drive malignant phenotypes in non-small cell lung cancer. Cancer Res 73:5402-15 (2013). PubMed: 23856247
  • Chou WW  et al. The role of SIRT1/AKT/ERK pathway in ultraviolet B induced damage on human retinal pigment epithelial cells. Toxicol In Vitro 27:1728-36 (2013). WB ; Human . PubMed: 23673314
  • Song Y  et al. Ephrin-A1 Is Up-Regulated by Hypoxia in Cancer Cells and Promotes Angiogenesis of HUVECs through a Coordinated Cross-Talk with eNOS. PLoS One 8:e74464 (2013). WB ; Human . PubMed: 24040255
  • Peng YF  et al. Autophagy inhibition suppresses pulmonary metastasis of HCC in mice via impairing anoikis resistance and colonization of HCC cells. Autophagy 9:2056-68 (2013). WB ; Human . PubMed: 24157892
  • Sobinoff AP  et al. Staying alive: PI3K pathway promotes primordial follicle activation and survival in response to 3MC-induced ovotoxicity. Toxicol Sci 128:258-71 (2012). PubMed: 22505044
  • Larive RM  et al. The Ras-like protein R-Ras2/TC21 is important for proper mammary gland development. Mol Biol Cell 23:2373-87 (2012). IHC-P ; Mouse . PubMed: 22535521
  • Wang CY  et al. Dehydrocostuslactone suppresses angiogenesis in vitro and in vivo through inhibition of Akt/GSK-3ß and mTOR signaling pathways. PLoS One 7:e31195 (2012). WB . PubMed: 22359572
  • Jang S  et al. Silver nanoparticles modify VEGF signaling pathway and mucus hypersecretion in allergic airway inflammation. Int J Nanomedicine 7:1329-43 (2012). WB ; Mouse . PubMed: 22457593
  • Kariya Y & Gu J N-glycosylation of ß4 integrin controls the adhesion and motility of keratinocytes. PLoS One 6:e27084 (2011). WB . PubMed: 22073258
  • Sobinoff AP  et al. Understanding the Villain: DMBA-induced preantral ovotoxicity involves selective follicular destruction and primordial follicle activation through PI3K/Akt and mTOR signaling. Toxicol Sci 123:563-75 (2011). IHC-P ; Mouse . PubMed: 21785161
  • Henken FE  et al. PIK3CA-mediated PI3-kinase signalling is essential for HPV-induced transformation in vitro. Mol Cancer 10:71 (2011). IHC-P ; Human . PubMed: 21663621
  • Hadchity E  et al. Heat shock protein 27 as a new therapeutic target for radiation sensitization of head and neck squamous cell carcinoma. Mol Ther 17:1387-94 (2009). WB ; Human . PubMed: 19436268

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