AF-DX 116 (Otenzepad), M2 antagonist (ab120152)
Key features and details
- M2 antagonist
- CAS Number: 102394-31-0
- Soluble in DMSO to 25 mM
- Form / State: Solid
- Source: Synthetic
製品の概要
-
製品名
AF-DX 116 (Otenzepad), M2 antagonist -
製品の詳細
M2 antagonist -
別名
- Otenzepad
-
生理活性の詳細
Selective M2 receptor antagonist.
-
CAS 番号
102394-31-0 -
構造式
製品の特性
-
体系名
11-[[2-[(Diethylamino)methyl]-1-piperidinyl]acetyl]-5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one -
分子量
421.54 -
分子式
C24H31N5O2 -
PubChem 登録番号
107867 -
保存方法
Store at Room Temperature. The product can be stored for up to 12 months. -
溶解性
Soluble in DMSO to 25 mM -
使用に関する注意
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Refer to SDS for further information
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
-
SMILES 線形表記
O=C(CN1CCCCC1CN(CC)CC)N4c2ccccc2C(=O)Nc3cccnc34 -
由来
Synthetic
-
研究分野
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
参考文献 (3)
ab120152 は 3 報の論文で使用されています。
- Tryon SC et al. Differential Regulation of Prelimbic and Thalamic Transmission to the Basolateral Amygdala by Acetylcholine Receptors. J Neurosci 43:722-735 (2023). PubMed: 36535767
- Choisy SC et al. Acute desensitization of acetylcholine and endothelin-1 activated inward rectifier K(+) current in myocytes from the cardiac atrioventricular node. Biochem Biophys Res Commun 423:496-502 (2012). PubMed: 22683635
- Gorini C et al. Endogenous inhibition of the trigeminally evoked neurotransmission to cardiac vagal neurons by muscarinic acetylcholine receptors. J Neurophysiol 104:1841-8 (2010). PubMed: 20719927