Anti-ACE2 抗体 (ab272690)
Key features and details
- Rabbit polyclonal to ACE2
- Suitable for: IHC-P
- Reacts with: Rat, Human
- Isotype: IgG
製品の概要
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製品名
Anti-ACE2 antibody
ACE2 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to ACE2 -
由来種
Rabbit -
Tested Applications & Species
See all applications and species dataApplication Species IHC-P RatHuman
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免疫原
Synthetic peptide corresponding to Human ACE2 aa 550-650 conjugated to keyhole limpet haemocyanin.
Database link: Q9BYF1 -
ポジティブ･コントロール
- IHC-P: human gastric carcinoma and rat pancreas tissue
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
バッファー
pH: 7.2
Preservative: 0.09% Sodium azide
Constituents: 1% BSA, 50% Glycerol (glycerin, glycerine) -
Concentration information loading... -
精製度
Protein A purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
アプリケーション
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab272690 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Tested applications are guaranteed to work and covered by our Abpromise guarantee.
Predicted to work for this combination of applications and species but not guaranteed.
Does not work for this combination of applications and species.
| アプリケーション | Species |
|---|---|
| IHC-P |
Rat
Human
|
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| IHC-P |
1/200 - 1/400.
|
| 特記事項 |
|---|
|
IHC-P
1/200 - 1/400. |
ターゲット情報
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機能
Carboxypeptidase which converts angiotensin I to angiotensin 1-9, a peptide of unknown function, and angiotensin II to angiotensin 1-7, a vasodilator. Also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. May be an important regulator of heart function. In case of human coronaviruses SARS and HCoV-NL63 infections, serve as functional receptor for the spike glycoprotein of both coronaviruses. -
組織特異性
Expressed in endothelial cells from small and large arteries, and in arterial smooth muscle cells. Expressed in lung alveolar epithelial cells, enterocytes of the small intestine, Leydig cells and Sertoli cells (at protein level). Expressed in heart, kidney, testis, and gastrointestinal system. -
配列類似性
Belongs to the peptidase M2 family. -
翻訳後修飾
N-glycosylation on Asn-90 may limit SARS infectivity. -
細胞内局在
Secreted and Cell membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 59272 Human
- Entrez Gene: 302668 Rat
- Omim: 300335 Human
- SwissProt: Q9BYF1 Human
- SwissProt: Q5EGZ1 Rat
- Unigene: 178098 Human
- Unigene: 129779 Rat
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別名
- ACE 2 antibody
- ACE related carboxypeptidase antibody
- ACE-related carboxypeptidase antibody
see all
画像
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ACE2 antibody (ab272690)
Formalin-fixed, paraffin embedded rat pancreas tissue stained for ACE2 using ab272690 at 1/200 in immunohistochemical analysis. DAB staining.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ACE2 antibody (ab272690)Formalin-fixed, paraffin embedded human gastric carcinoma tissue stained for ACE2 using ab272690 at 1/200 in immunohistochemical analysis. DAB staining.
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
参考文献 (0)
ab272690 は論文での使用が確認できていません。
