Key features and details
- Goat polyclonal to ABCB5
- Suitable for: WB
- Isotype: IgG
ABCB5 一次抗体 製品一覧
交差が予測される動物種: Mouse, Human
C-DKKPSIDNFSTAGYK(with a Cysteine residue linker), corresponding to internal sequence amino acids 364-378 of Human ABCB5 (NP_001157413.1; NP_848654.3; NP_001157414.1; NP_001157465.1; A7BKA4) The immunizing peptide represents part of an extracellular domain.
- Hela cell lysate and K562 cell lysate
保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Preservative: 0.02% Sodium azide
Constituents: 99% Tris buffered saline, 0.5% BSA
Concentration information loading...
精製度Immunogen affinity purified
特記事項（精製）Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
|WB||Use at an assay dependent concentration. Predicted molecular weight: 139 kDa.
A 1 hour primary incubation is recommended for this product. Preliminary experiments gave an approx 85kDa band observed in lysates of cell lines HeLa and K562 (calculated MW of 139kDa according to NP_001157413.1). Please note that the isoform recognized by this antibody is not fully understood. We appreciate any feedback in the field on these results.
機能Plasma membrane transporter able to mediate efflux from cells of the rhodamine dye and of the therapeutic drug doxorubicin. Responsible for the resistance to doxorubicin of a subset of malignant melanomas.
組織特異性Expressed by CD133-expressing progenitor cells among epidermal melanocytes (at protein level). Widely expressed with specific expression in pigment cells. Also expressed in several malignant tissues.
配列類似性Belongs to the ABC transporter superfamily. ABCB family. Multidrug resistance exporter (TC 3.A.1.201) subfamily.
Contains 1 ABC transmembrane type-1 domain.
Contains 2 ABC transporter domains.
- Information by UniProt
- ABCB 5 antibody
- ABCB5 antibody
- ABCB5 P-gp antibody