GNAI1 + GNAI2 peptide (ab5006)
Key features and details
- Purity: > 70% HPLC
- Suitable for: Blocking
製品の詳細
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製品名
GNAI1 + GNAI2 peptide -
精製度
> 70 % HPLC.
Peptides are analyzed by Reverse-Phase HPLC (RP-HPLC) in order to determine purity. Identities are confirmed by MALDI-MS. -
Animal free
No -
由来
Synthetic
関連製品
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Related Products
特性
Our Abpromise guarantee covers the use of ab5006 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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アプリケーション
Blocking
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製品の状態
Lyophilized -
備考
This peptide may be used for neutralization and control experiments with the polyclonal antibody that reacts with this product and human G protein alpha inhibitor 1/2, catalog ab3522. Using a solution of peptide of equal volume and concentration to the corresponding antibody will yield a large molar excess of peptide (~ 70-fold) for competitive inhibition of antibody-protein binding reactions.
This product was previously labelled as G protein alpha inhibitor 1, G Protein alpha Inhibitor 1+2
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Concentration information loading...
前処理および保存
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保存方法および安定性
Shipped at 4°C. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
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再構成>95% pure, lyophilized synthetic peptide. Reconstitute with 0.1 ml of distilled water.
関連情報
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別名
- Adenylate cyclase-inhibiting G alpha protein
- Gi
- Gi1 protein alpha subunit
see all -
機能
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta-adrenergic stimuli. The inactive GDP-bound form prevents the association of RGS14 with centrosomes and is required for the translocation of RGS14 from the cytoplasm to the plasma membrane. May play a role in cell division. -
配列類似性
Belongs to the G-alpha family. G(i/o/t/z) subfamily. -
細胞内局在
Nucleus. Cytoplasm. Cell membrane. Cytoplasm > cytoskeleton > centrosome. Localized at the plasma membrane throughout mitosis. Colocalizes with RIC8A and RGS14 at the plasma membrane (By similarity). Localizes in the centrosomes of interphase and mitotic cells, but not in centrosomes during cytokinesis. Detected at the cleavage furrow or the midbody. - Information by UniProt
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
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Datasheet download
参考文献 (0)
ab5006 は論文での使用が確認できていません。