AANAT peptide (ab5004)
Key features and details
- Purity: > 95% HPLC
- Suitable for: Blocking
製品の詳細
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製品名
AANAT peptide
AANAT タンパク質・ペプチド 製品一覧 -
精製度
> 95 % HPLC.
Peptides are analyzed by Reverse-Phase HPLC (RP-HPLC) in order to determine purity. Identities are confirmed by MALDI-MS. -
Animal free
No -
由来
Synthetic
関連製品
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Related Products
特性
Our Abpromise guarantee covers the use of ab5004 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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アプリケーション
Blocking
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製品の状態
Lyophilized -
備考
This peptide may be used for neutralization and control experiments with the polyclonal antibody that reacts with this product and AA-NAT, catalog ab3506. Using a solution of peptide of equal volume and concentration to the corresponding antibody will yield a large molar excess of peptide (~ 70-fold) for competitive inhibition of antibody-protein binding reactions.
This product was previously labelled as Serotonin N-acetyltransferase
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Concentration information loading...
前処理および保存
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保存方法および安定性
Shipped at 4°C. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
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再構成>95% pure, lyophilized synthetic peptide. Reconstitute with 0.1 ml of distilled water.
関連情報
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別名
- AA-NAT
- Aanat
- Aralkylamine N-acetyltransferase
see all -
機能
Controls the night/day rhythm of melatonin production in the pineal gland. Catalyzes the N-acetylation of serotonin into N-acetylserotonin, the penultimate step in the synthesis of melatonin. -
組織特異性
Highly expressed in pineal gland and at lower levels in the retina. Weak expression in several brain regions and in the pituitary gland. -
パスウェイ
Aromatic compound metabolism; melatonin biosynthesis; melatonin from serotonin: step 1/2. -
関連疾患
Delayed sleep phase syndrome -
配列類似性
Belongs to the acetyltransferase family. AANAT subfamily.
Contains 1 N-acetyltransferase domain. -
翻訳後修飾
cAMP-dependent phosphorylation on both N-terminal Thr-31 and C-terminal Ser-205 regulates AANAT activity by promoting interaction with 14-3-3 proteins. -
細胞内局在
Cytoplasm. - Information by UniProt
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
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Datasheet download
参考文献 (0)
ab5004 は論文での使用が確認できていません。