Recombinant Human TLR2 protein (His tag) (ab222352)
Key features and details
- Expression system: Baculovirus infected insect cells
- Purity: > 90% SDS-PAGE
- Endotoxin level: < 1.000 Eu/µg
- Tags: His tag C-Terminus
- Suitable for: SDS-PAGE
製品の詳細
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製品名
Recombinant Human TLR2 protein (His tag)
TLR2 タンパク質・ペプチド 製品一覧 -
精製度
> 90 % SDS-PAGE.
Affinity purified -
エンドトキシン・レベル
< 1.000 Eu/µg -
発現系
Baculovirus infected insect cells -
アクセッション番号
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タンパク質長
Protein fragment -
Animal free
No -
由来
Recombinant -
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生物種
Human -
配列
KEESSNQASLSCDRNGICKGSSGSLNSIPSGLTEAVKSLDLSNNRITYIS NSDLQRCVNLQALVLTSNGINTIEEDSFSSLGSLEHLDLSYNYLSNLSSS WFKPLSSLTFLNLLGNPYKTLGETSLFSHLTKLQILRVGNMDTFTKIQRK DFAGLTFLEELEIDASDLQSYEPKSLKSIQNVSHLILHMKQHILLLEIFV DVTSSVECLELRDTDLDTFHFSELSTGETNSLIKKFTFRNVKITDESLFQ VMKLLNQISGLLELEFDDCTLNGVGNFRASDNDRVIDPGKVETLTIRRLH IPRFYLFYDLSTLYSLTERVKRITVENSKVFLVPCLLSQHLKSLEYLDLS ENLMVEEYLKNSACEDAWPSLQTLILRQNHLASLEKTGETLLTLKNLTNI DISKNSFHSMPETCQWPEKMKYLNLSSTRIHSVTGCIPKTLEILDVSNNN LNLFSLNLPQLKELYISRNKLMTLPDASLLPMLLVLKISRNAITTFSKEQ LDSFHTLKTLEAGGNNFICSCEFLSFTQEQQALAKVLIDWPANYLCDSPS HVRGQQVQDVRLSVSECHRTLEHHHHHH -
予測される分子量
66 kDa including tags -
領域
19 to 588 -
タグ
His tag C-Terminus -
配列の追加情報
NP_003255.
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関連製品
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Related Products
特性
Our Abpromise guarantee covers the use of ab222352 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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アプリケーション
SDS-PAGE
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製品の状態
Liquid -
Concentration information loading...
前処理および保存
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保存方法および安定性
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
pH: 7.40
Constituents: 10% Glycerol (glycerin, glycerine), PBS
関連情報
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別名
- CD282
- CD282 antigen
- TIL 4
see all -
機能
Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. May also promote apoptosis in response to lipoproteins. Recognizes mycoplasmal macrophage-activating lipopeptide-2kD (MALP-2), soluble tuberculosis factor (STF), phenol-soluble modulin (PSM) and B.burgdorferi outer surface protein A lipoprotein (OspA-L) cooperatively with TLR6. -
組織特異性
Highly expressed in peripheral blood leukocytes, in particular in monocytes, in bone marrow, lymph node and in spleen. Also detected in lung and in fetal liver. Levels are low in other tissues. -
配列類似性
Belongs to the Toll-like receptor family.
Contains 14 LRR (leucine-rich) repeats.
Contains 1 TIR domain. -
翻訳後修飾
Glycosylation of Asn-442 is critical for secretion of the N-terminal ectodomain of TLR2. -
細胞内局在
Membrane. - Information by UniProt
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (0)
ab222352 は論文での使用が確認できていません。