Recombinant Human Insulin degrading enzyme / IDE protein (ab152467)
Key features and details
- Expression system: Wheat germ
- Suitable for: WB, SDS-PAGE, ELISA
製品の詳細
-
製品名
Recombinant Human Insulin degrading enzyme / IDE protein
Insulin degrading enzyme / IDE タンパク質・ペプチド 製品一覧 -
発現系
Wheat germ -
アクセッション番号
-
タンパク質長
Protein fragment -
Animal free
No -
由来
Recombinant -
-
生物種
Human -
配列
RDNTEVAYLKTLTKEDIIKFYKEMLAVDAPRRHKVSVHVLAREMDSCPVV GEFPCQNDINLSQAPALPQPEVIQNMTEFKRGLPLFPLVKPHINFMAAKL -
予測される分子量
37 kDa including tags -
領域
920 to 1019
-
関連製品
-
Related Products
特性
Our Abpromise guarantee covers the use of ab152467 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
-
アプリケーション
Western blot
SDS-PAGE
ELISA
-
製品の状態
Liquid -
備考
-
Concentration information loading...
前処理および保存
-
保存方法および安定性
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00
Constituents: 0.31% Glutathione, 0.79% Tris HCl
関連情報
-
別名
- Abeta-degrading protease
- FLJ35968
- Ide
see all -
機能
Plays a role in the cellular breakdown of insulin, IAPP, glucagon, bradykinin, kallidin and other peptides, and thereby plays a role in intercellular peptide signaling. Degrades amyloid formed by APP and IAPP. May play a role in the degradation and clearance of naturally secreted amyloid beta-protein by neurons and microglia. -
配列類似性
Belongs to the peptidase M16 family. -
翻訳後修飾
The N-terminus is blocked. -
細胞内局在
Cytoplasm. Cell surface. Present at the cell surface of neuron cells. The membrane-associated isoform is approximately 5 kDa larger than the known cytosolic isoform. - Information by UniProt
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
-
Datasheet download
参考文献 (0)
ab152467 は論文での使用が確認できていません。