Anti-MVD 抗体 [EPR6559(2)] (ab129061)
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EPR6559(2)] to MVD
- Suitable for: WB
- Reacts with: Human
Related conjugates and formulations
製品の概要
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製品名
Anti-MVD antibody [EPR6559(2)]
MVD 一次抗体 製品一覧 -
製品の詳細
Rabbit monoclonal [EPR6559(2)] to MVD -
由来種
Rabbit -
アプリケーション
適用あり: WBmore details
適用なし: Flow Cyt,ICC/IF,IHC-P or IP -
種交差性
交差種: Human -
免疫原
Synthetic peptide within Human MVD aa 250-350. The exact sequence is proprietary.
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ポジティブ・コントロール
- Human fetal liver, K562 and HepG2 lysates.
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特記事項
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C. -
解離定数(KD 値)
KD = 2.34 x 10 -10 M Learn more about KD -
バッファー
pH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 9% PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA, 50% Tissue culture supernatant -
Concentration information loading...
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精製度
Protein A purified -
ポリ/モノ
モノクローナル -
クローン名
EPR6559(2) -
アイソタイプ
IgG -
研究分野
関連製品
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Alternative Versions
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab129061の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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WB | (1) |
1/1000 - 1/10000. Detects a band of approximately 43 kDa (predicted molecular weight: 43 kDa).
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特記事項 |
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WB
1/1000 - 1/10000. Detects a band of approximately 43 kDa (predicted molecular weight: 43 kDa). |
ターゲット情報
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機能
Performs the first committed step in the biosynthesis of isoprenes. -
組織特異性
Expressed in heart, skeletal muscle, lung, liver, brain, pancreas, kidney and placenta. -
パスウェイ
Steroid biosynthesis; cholesterol biosynthesis. -
配列類似性
Belongs to the diphosphomevalonate decarboxylase family. - Information by UniProt
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参照データベース
- Entrez Gene: 4597 Human
- Omim: 603236 Human
- SwissProt: P53602 Human
- Unigene: 252457 Human
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別名
- Diphosphomevalonate decarboxylase antibody
- FP17780 antibody
- MDDase antibody
see all
画像
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All lanes : Anti-MVD antibody [EPR6559(2)] (ab129061) at 1/1000 dilution
Lane 1 : Human fetal liver lysate
Lane 2 : K562 cell lysate
Lane 3 : HepG2 cell lysate
Lysates/proteins at 10 µg per lane.
Secondary
All lanes : Goat anti-rabbit HRP at 1/2000 dilution
Predicted band size: 43 kDa
Observed band size: 43 kDa
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (2)
ab129061 は 2 報の論文で使用されています。
- Buchou C et al. Upregulation of the Mevalonate Pathway through EWSR1-FLI1/EGR2 Regulatory Axis Confers Ewing Cells Exquisite Sensitivity to Statins. Cancers (Basel) 14:N/A (2022). PubMed: 35565457
- Zhang P et al. Intrinsic BET inhibitor resistance in SPOP-mutated prostate cancer is mediated by BET protein stabilization and AKT-mTORC1 activation. Nat Med 23:1055-1062 (2017). PubMed: 28805822