1-EBIO, Activator of Ca2+-activated K+ channels and CFTR channels (ab120258)
Key features and details
- Activator of Ca2+-activated K+ channels and CFTR channels
- CAS Number: 10045-45-1
- Soluble in DMSO to 100 mM and in ethanol to 100 mM
- Form / State: Solid
- Source: Synthetic
製品の概要
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製品名
1-EBIO, Activator of Ca2+-activated K+ channels and CFTR channels -
製品の詳細
Activator of Ca2+-activated K+ channels and CFTR channels -
別名
- IK channel
- SK channel
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生理活性の詳細
Activator of small and intermediate conductance Ca2+ activated K+ channels (SK). Also activates apical membrane Cl- conductance CFTR channel.
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CAS 番号
10045-45-1 -
構造式
製品の特性
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体系名
1-Ethyl-1,3-dihydro-2H-benzimidazol-2-one -
分子量
162.19 -
分子式
C9H10N2O -
PubChem 登録番号
82320 -
保存方法
Store at Room Temperature. The product can be stored for up to 12 months. -
溶解性
Soluble in DMSO to 100 mM and in ethanol to 100 mM -
使用に関する注意
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Refer to SDS for further information
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES 線形表記
O=C2Nc1ccccc1N2CC -
由来
Synthetic
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研究分野
画像
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
参考文献 (3)
ab120258 は 3 報の論文で使用されています。
- Jia X et al. Functional cooperation between IKCa and TRPC1 channels regulates serum-induced vascular smooth muscle cell proliferation via mediating Ca2+ influx and ERK1/2 activation. Cell Prolif 56:e13385 (2023). PubMed: 36562293
- Tonini R et al. Small-conductance Ca2+-activated K+ channels modulate action potential-induced Ca2+ transients in hippocampal neurons. J Neurophysiol 109:1514-24 (2013). PubMed: 23255726
- Atchley D et al. Pharmacological enhancement of calcium-activated potassium channel function reduces the effects of repeated stress on fear memory. Behav Brain Res 232:37-43 (2012). PubMed: 22487247