Anti-P70 S6 Kinase beta/SRK (phospho S371) 抗体 [EPR2132] (ab109393)
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EPR2132] to P70 S6 Kinase beta/SRK (phospho S371)
- Suitable for: WB
- Reacts with: Human
Related conjugates and formulations
製品の概要
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製品名
Anti-P70 S6 Kinase beta/SRK (phospho S371) antibody [EPR2132]
P70 S6 Kinase beta/SRK 一次抗体 製品一覧 -
製品の詳細
Rabbit monoclonal [EPR2132] to P70 S6 Kinase beta/SRK (phospho S371) -
由来種
Rabbit -
特異性
This antibody only detects p70 S6 Kinase phosphorylated at serine 371. -
アプリケーション
適用あり: WBmore details
適用なし: Flow Cyt,ICC/IF,IHC-P or IP -
種交差性
交差種: Human
交差が予測される動物種: Mouse, Rat -
免疫原
Synthetic peptide. This information is proprietary to Abcam and/or its suppliers.
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ポジティブ・コントロール
- 293T cell lysate treated with Alkaline Phosphatase (AP).
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特記事項
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C. -
バッファー
pH: 7.20
Preservative: 0.05% Sodium azide
Constituents: 0.1% BSA, 40% Glycerol (glycerin, glycerine), 9.85% Tris glycine, 50% Tissue culture supernatant -
Concentration information loading...
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精製度
Protein A purified -
ポリ/モノ
モノクローナル -
クローン名
EPR2132 -
アイソタイプ
IgG -
研究分野
関連製品
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Alternative Versions
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab109393の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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WB |
1/1000 - 1/10000. Predicted molecular weight: 53 kDa.
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特記事項 |
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WB
1/1000 - 1/10000. Predicted molecular weight: 53 kDa. |
ターゲット情報
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機能
Phosphorylates specifically ribosomal protein S6. -
配列類似性
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.
Contains 1 AGC-kinase C-terminal domain.
Contains 1 protein kinase domain. -
翻訳後修飾
Phosphorylated upon DNA damage, probably by ATM or ATR. - Information by UniProt
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参照データベース
- Entrez Gene: 6199 Human
- Entrez Gene: 58988 Mouse
- Entrez Gene: 361696 Rat
- Omim: 608939 Human
- SwissProt: Q9UBS0 Human
- SwissProt: Q9Z1M4 Mouse
- Unigene: 534345 Human
- Unigene: 271937 Mouse
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別名
- 70 kDa ribosomal protein S6 kinase 2 antibody
- EC 2.7.11.1 antibody
- KS6B2_HUMAN antibody
see all
画像
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (17)
ab109393 は 17 報の論文で使用されています。
- Chen B et al. SHANK1 facilitates non-small cell lung cancer processes through modulating the ubiquitination of Klotho by interacting with MDM2. Cell Death Dis 13:403 (2022). PubMed: 35468874
- Zhang LJ et al. miR-513b-5p inhibits the proliferation and promotes apoptosis of retinoblastoma cells by targeting TRIB1. Open Med (Wars) 16:1364-1371 (2021). PubMed: 34589612
- Guo Y et al. Spontaneous formation of neutrophil extracellular traps is associated with autophagy. Sci Rep 11:24005 (2021). PubMed: 34907287
- Dang N et al. α5-nAChR modulates melanoma growth through the Notch1 signaling pathway. J Cell Physiol 235:7816-7826 (2020). PubMed: 31907929
- Wei W et al. miR-600 inhibits lung cancer via downregulating the expression of METTL3. Cancer Manag Res 11:1177-1187 (2019). PubMed: 30774445