Anti-VTA1 抗体 (ab96738)
Key features and details
- Rabbit polyclonal to VTA1
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
製品の概要
-
製品名
Anti-VTA1 antibody -
製品の詳細
Rabbit polyclonal to VTA1 -
由来種
Rabbit -
アプリケーション
適用あり: WB, IHC-Pmore details -
種交差性
交差種: Human
交差が予測される動物種: Mouse, Rat, Cow -
免疫原
Recombinant fragment, corresponding to a sequence within amino acids 1-246 of Human VTA1
-
ポジティブ・コントロール
- H1299, HeLaS3, Molt4 whole cell lysates; SW480 xenograft tissue.
-
特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
-
製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
バッファー
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 10% Glycerol (glycerin, glycerine) -
Concentration information loading...
-
精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
-
Compatible Secondaries
-
Isotype control
-
Positive Controls
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab96738の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
---|---|---|
WB |
1/500 - 1/3000. Predicted molecular weight: 34 kDa.
|
|
IHC-P |
1/100 - 1/500.
|
特記事項 |
---|
WB
1/500 - 1/3000. Predicted molecular weight: 34 kDa. |
IHC-P
1/100 - 1/500. |
ターゲット情報
-
機能
Involved in the endosomal multivesicular bodies (MVB) pathway. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. Thought to be a cofactor of VPS4A/B, which catalyzes disassembles membrane-associated ESCRT-III assemblies. Involved in the sorting and down-regulation of EGFR (By similarity). Involved in HIV-1 budding. -
配列類似性
Belongs to the VTA1 family. -
細胞内局在
Cytoplasm. Endosome membrane. - Information by UniProt
-
参照データベース
- Entrez Gene: 506430 Cow
- Entrez Gene: 51534 Human
- Entrez Gene: 66201 Mouse
- Entrez Gene: 292640 Rat
- Omim: 610902 Human
- SwissProt: Q32L63 Cow
- SwissProt: Q9NP79 Human
- SwissProt: Q9CR26 Mouse
see all -
別名
- C6orf55 antibody
- Chromosome 6 open reading frame 55 antibody
- Dopamine responsive protein DRG 1 antibody
see all
画像
-
All lanes : Anti-VTA1 antibody (ab96738) at 1/1000 dilution
Lane 1 : H1299 whole cell lysate
Lane 2 : HeLaS3 whole cell lysate
Lane 3 : Molt4 whole cell lysate
Lysates/proteins at 30 µg per lane.
Predicted band size: 34 kDa
12% SDS-PAGE. -
ab96738 at 1/500 dilution staining VTA1 in SW480 xenograft by Immunohistochemistry, Paraffin-embedded tissue.
プロトコール
データシートおよび資料
-
SDS download
-
Datasheet download
参考文献 (0)
ab96738 は論文での使用が確認できていません。