Anti-SAF-B2 抗体 [6F7] (ab67344)
Key features and details
- Mouse monoclonal [6F7] to SAF-B2
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG1
製品の概要
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製品名
Anti-SAF-B2 antibody [6F7]
SAF-B2 一次抗体 製品一覧 -
製品の詳細
Mouse monoclonal [6F7] to SAF-B2 -
由来種
Mouse -
アプリケーション
適用あり: IHC-Pmore details -
種交差性
交差種: Human -
免疫原
Synthetic peptide corresponding to Human SAF-B2 aa 345-357.
Sequence:PEARDSKEDGRKF
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ポジティブ・コントロール
- Human brain cortex tissue.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot. Store at -20°C. Avoid freeze / thaw cycle. -
バッファー
pH: 7.4
Constituent: PBS -
Concentration information loading...
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精製度
Protein G purified -
ポリ/モノ
モノクローナル -
クローン名
6F7 -
アイソタイプ
IgG1 -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab67344の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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IHC-P |
特記事項 |
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IHC-P: Use at a concentration of 5 µg/ml.
IP: Use at an assay dependent dilution.
WB: Use at an assay dependent dilution. Predicted molecular weight: 108 kDa.
N.B. on SDS PAGE gels, Scaffold attachment factor B2 runs as an approximately 130 kDa protein. This aberrant migration is due to a large number of charged amino acid residues.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
ターゲット情報
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機能
Binds to scaffold/matrix attachment region (S/MAR) DNA. Can function as an estrogen receptor corepressor and can also inhibit cell proliferation. -
組織特異性
Expressed at high levels in the CNS and at low levels in the liver. Expressed in a wide number of breast cancer cell lines. -
配列類似性
Contains 1 RRM (RNA recognition motif) domain.
Contains 1 SAP domain. -
翻訳後修飾
Phosphorylated upon DNA damage, probably by ATM or ATR. -
細胞内局在
Cytoplasm. Nucleus. - Information by UniProt
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参照データベース
- Entrez Gene: 9667 Human
- Omim: 608066 Human
- SwissProt: Q14151 Human
- Unigene: 655392 Human
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別名
- DKFZP779C1727 antibody
- HAP antibody
- HET antibody
see all
画像
データシートおよび資料
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Datasheet download
参考文献 (0)
ab67344 は論文での使用が確認できていません。