Anti-SCGN/Secretagogin 抗体 (ab111871)
Key features and details
- Rabbit polyclonal to SCGN/Secretagogin
- Suitable for: WB, ICC/IF
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-SCGN/Secretagogin antibody
SCGN/Secretagogin 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to SCGN/Secretagogin -
由来種
Rabbit -
アプリケーション
適用あり: WB, ICC/IFmore details -
種交差性
交差種: Human
交差が予測される動物種: Mouse, Rat, Cow -
免疫原
Recombinant fragment corresponding to Human SCGN/Secretagogin aa 57-238. (AAH00336)
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ポジティブ・コントロール
- HeLa and HCT116 cells and whole cell lysates.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
バッファー
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 78.99% PBS, 1% BSA, 20% Glycerol (glycerin, glycerine) -
Concentration information loading...
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精製度
Immunogen affinity purified -
特記事項(精製)
ab111871 is purified by antigen-affinity chromatography. -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Positive Controls
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab111871の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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WB |
1/500 - 1/3000. Predicted molecular weight: 32 kDa.
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ICC/IF |
1/100 - 1/500.
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特記事項 |
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WB
1/500 - 1/3000. Predicted molecular weight: 32 kDa. |
ICC/IF
1/100 - 1/500. |
ターゲット情報
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組織特異性
Expressed at high levels in the pancreatic islets of Langerhans and to a much lesser extent in the gastrointestinal tract (stomach, small intestine and colon), the adrenal medulla and cortex and the thyroid C-cells. In the brain, the expression is restricted to distinct subtypes of neurons with highest expression in the molecular layer of the cerebellum (stellate and basket cells), in the anterior part of the pituitary gland, in the thalamus, in the hypothalamus and in a subgroup of neocortical neurons. -
配列類似性
Contains 6 EF-hand domains. -
細胞内局在
Cytoplasm. Secreted. Cytoplasmic vesicle > secretory vesicle membrane. Predominantly cytoplasmic. A small proportion is associated with secretory granules and membrane fractions (By similarity). Detectable in human serum after ischemic neuronal damage. - Information by UniProt
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参照データベース
- Entrez Gene: 618206 Cow
- Entrez Gene: 10590 Human
- Entrez Gene: 214189 Mouse
- Entrez Gene: 306942 Rat
- Omim: 609202 Human
- SwissProt: A5PJN0 Cow
- SwissProt: O76038 Human
- SwissProt: Q91WD9 Mouse
see all -
別名
- Calbindin like antibody
- CALBL antibody
- DJ501N12.8 antibody
see all
画像
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (3)
ab111871 は 3 報の論文で使用されています。
- Shi Y et al. Mouse and human share conserved transcriptional programs for interneuron development. Science 374:eabj6641 (2021). PubMed: 34882453
- Garas FN et al. Structural and molecular heterogeneity of calretinin-expressing interneurons in the rodent and primate striatum. J Comp Neurol 526:877-898 (2018). Mouse . PubMed: 29218729
- Garas FN et al. Secretagogin expression delineates functionally-specialized populations of striatal parvalbumin-containing interneurons. Elife 5:N/A (2016). PubMed: 27669410