Recombinant Human Metnase protein (ab125543)
Key features and details
- Expression system: Baculovirus infected Sf9 cells
- Purity: > 85% SDS-PAGE
- Suitable for: SDS-PAGE
製品の詳細
-
製品名
Recombinant Human Metnase protein
Metnase タンパク質・ペプチド 製品一覧 -
精製度
> 85 % SDS-PAGE.
Purity was determined to be >85% by densitometry. Affinity purified. -
発現系
Baculovirus infected Sf9 cells -
アクセッション番号
-
タンパク質長
Full length protein -
Animal free
No -
由来
Recombinant -
-
生物種
Human -
予測される分子量
69 kDa including tags -
領域
1 to 671
-
関連製品
-
Related Products
特性
Our Abpromise guarantee covers the use of ab125543 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
-
アプリケーション
SDS-PAGE
-
製品の状態
Liquid -
備考
Previously labelled as SETMAR.
-
Concentration information loading...
前処理および保存
-
保存方法および安定性
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 7.50
Constituents: 0.31% Glutathione, 0.002% PMSF, 0.004% DTT, 0.79% Tris HCl, 0.003% EDTA, 25% Glycerol (glycerin, glycerine), 0.88% Sodium chloride
関連情報
-
別名
- Histone lysine N methyltransferase
- Histone lysine N methyltransferase SETMAR
- Hsmar 1
see all -
機能
Histone methyltransferase that methylates 'Lys-4' and 'Lys-36' of histone H3, 2 specific tags for epigenetic transcriptional activation. Specifically mediates dimethylation of H3 'Lys-36'. Has sequence-specific DNA-binding activity and recognizes the 19-mer core of the 5'-terminal inverted repeats (TIRs) of the Hsmar1 element. Has DNA nicking activity. Has in vivo end joining activity and may mediate genomic integration of foreign DNA. -
組織特異性
Widely expressed, with highest expression in placenta and ovary and lowest expression in skeletal muscle. -
配列類似性
In the N-terminal section; belongs to the histone-lysine methyltransferase family.
In the C-terminal section; belongs to the mariner transposase family.
Contains 1 post-SET domain.
Contains 1 pre-SET domain.
Contains 1 SET domain. -
ドメイン
The mariner transposase Hsmar1 region mediates DNA-binding. It has no transposase activity because the active site contains an Asn in position 610 instead of a Asp residue. -
細胞内局在
Nucleus. Chromosome. - Information by UniProt
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
-
SDS download
-
Datasheet download
参考文献 (0)
ab125543 は論文での使用が確認できていません。