Kynurenic acid sodium salt, Endogenous ionotropic / nicotinic antagonist (ab120256)
Key features and details
- Endogenous ionotropic / nicotinic antagonist; water soluble
- CAS Number: 2439-02-3
Soluble in water to 100 mM
- Form / State: Solid
- Source: Synthetic
製品の概要
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製品名
Kynurenic acid sodium salt, Endogenous ionotropic / nicotinic antagonist -
製品の詳細
Endogenous ionotropic / nicotinic antagonist; water soluble -
生理活性の詳細
Endogenous antagonist at ionotropic, glycine and α7 nicotinic receptors. Neuroprotective in vivo. Water soluble form.
Also available in simple stock solutions (ab146693) - add 1 ml of water to get an exact, ready-to-use concentration. -
CAS 番号
2439-02-3 -
構造式
製品の特性
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体系名
4-Hydroxyquinoline-2-carboxylic acid sodium salt
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分子量
211.15 -
分子式
C10H6NNaO3 -
PubChem 登録番号
52974250 -
保存方法
Store at Room Temperature. Store under desiccating conditions. The product can be stored for up to 12 months. -
溶解性
Soluble in water to 100 mM
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使用に関する注意
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES 線形表記
O=C(O[Na])c1cc(O)c2ccccc2n1 -
由来
Synthetic
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研究分野
関連製品
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プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
参考文献 (14)
ab120256 は 14 報の論文で使用されています。
- Liu M et al. Make war not love: The neural substrate underlying a state-dependent switch in female social behavior. Neuron 110:841-856.e6 (2022). PubMed: 34982958
- Merlaud Z et al. Conformational state-dependent regulation of GABAA receptor diffusion and subsynaptic domains. iScience 25:105467 (2022). PubMed: 36388998
- McElvain LE et al. Specific populations of basal ganglia output neurons target distinct brain stem areas while collateralizing throughout the diencephalon. Neuron 109:1721-1738.e4 (2021). PubMed: 33823137
- Yu W et al. Periaqueductal gray/dorsal raphe dopamine neurons contribute to sex differences in pain-related behaviors. Neuron 109:1365-1380.e5 (2021). PubMed: 33740416
- Vaden JH et al. The readily-releasable pool dynamically regulates multivesicular release. Elife 8:N/A (2019). PubMed: 31364987