Anti-DPEP1/MDP 抗体 (ab121308)
Key features and details
- Rabbit polyclonal to DPEP1/MDP
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
リコンビナント抗体で、ロット間での高い再現性を実現
- 異なるロット間での安定した再現性
- 容易なスケールアップ
- 評価試験による特異性の確認済み
- 倫理基準に準拠 - アニマル・フリーの生産
製品の概要
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製品名
Anti-DPEP1/MDP antibody
DPEP1/MDP 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to DPEP1/MDP -
由来種
Rabbit -
アプリケーション
適用あり: WB, IHC-Pmore details -
種交差性
交差種: Human -
免疫原
Recombinant fragment corresponding to Human DPEP1/MDP aa 263-388.
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ポジティブ・コントロール
- IHC: Human Plasma lysate; Human small intestine tissue.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
バッファー
pH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 59% PBS, 40% Glycerol (glycerin, glycerine) -
Concentration information loading...
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精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab121308の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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WB |
Use a concentration of 0.04 - 0.4 µg/ml. Predicted molecular weight: 46 kDa.
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IHC-P |
1/1000 - 1/2500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
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特記事項 |
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WB
Use a concentration of 0.04 - 0.4 µg/ml. Predicted molecular weight: 46 kDa. |
IHC-P
1/1000 - 1/2500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
ターゲット情報
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機能
Hydrolyzes a wide range of dipeptides. Implicated in the renal metabolism of glutathione and its conjugates. Converts leukotriene D4 to leukotriene E4; it may play an important role in the regulation of leukotriene activity. -
配列類似性
Belongs to the peptidase M19 family. -
細胞内局在
Apical cell membrane. Cell projection > microvillus membrane. Brush border membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 1800 Human
- Omim: 179780 Human
- SwissProt: P16444 Human
- Unigene: 109 Human
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別名
- Dehydropeptidase-I antibody
- Dipeptidase 1 (renal) antibody
- Dipeptidase 1 antibody
see all
画像
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All lanes : Anti-DPEP1/MDP antibody (ab121308) at 0.4 µg/ml
Lane 1 : Control - vector only transfected HEK293T lysate
Lane 2 : DPEP1 over-expression lysate - co-expressed with a C-terminal myc-DDY tag (3.1kDa)
Predicted band size: 46 kDa -
ab121308 at 1/2500 dilution staining DPEP1/MDP in Paraffin-embedded Human kidney tissue by Immunohistochemistry.
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ab121308 at 1/2500 dilution staining DPEP1/MDP in Paraffin-embedded Human lymp node tissue by Immunohistochemistry. This shows low expresion as expected.
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ab121308 at 1/2500 dilution staining DPEP1/MDP in Paraffin-embedded Human small intestine tissue by Immunohistochemistry.
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (2)
ab121308 は 2 報の論文で使用されています。
- Lau A et al. Dipeptidase-1 governs renal inflammation during ischemia reperfusion injury. Sci Adv 8:eabm0142 (2022). PubMed: 35108057
- Choudhury SR et al. Dipeptidase-1 Is an Adhesion Receptor for Neutrophil Recruitment in Lungs and Liver. Cell 178:1205-1221.e17 (2019). PubMed: 31442408