Anti-CYP26A1 抗体 (ab151968)
Key features and details
- Rabbit polyclonal to CYP26A1
- Suitable for: WB, IHC-P
- Reacts with: Mouse, Human
- Isotype: IgG
リコンビナント抗体で、ロット間での高い再現性を実現
- 異なるロット間での安定した再現性
- 容易なスケールアップ
- 評価試験による特異性の確認済み
- 倫理基準に準拠 - アニマル・フリーの生産
製品の概要
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製品名
Anti-CYP26A1 antibody
CYP26A1 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to CYP26A1 -
由来種
Rabbit -
アプリケーション
適用あり: WB, IHC-Pmore details -
種交差性
交差種: Mouse, Human
交差が予測される動物種: Rat, Cow, Monkey -
免疫原
Recombinant fragment, corresponding to a region within amino acids 246-497 of Human CYP26A1 (O43174).
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ポジティブ・コントロール
- 293T whole cell lysate; Human hepatoma and Mouse muscle tissues.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
バッファー
pH: 7.00
Preservative: 0.025% Proclin 300
Constituents: 79% PBS, 20% Glycerol (glycerin, glycerine) -
Concentration information loading...
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精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab151968の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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WB |
1/500 - 1/3000. Predicted molecular weight: 56 kDa.
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IHC-P |
1/100 - 1/1000. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
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特記事項 |
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WB
1/500 - 1/3000. Predicted molecular weight: 56 kDa. |
IHC-P
1/100 - 1/1000. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
ターゲット情報
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機能
Plays a key role in retinoic acid metabolism. Acts on retinoids, including all-trans-retinoic acid (RA) and its stereoisomer 9-cis-RA. Capable of both 4-hydroxylation and 18-hydroxylation. Responsible for generation of several hydroxylated forms of RA, including 4-OH-RA, 4-oxo-RA and 18-OH-RA. -
組織特異性
Highest levels in adult liver, heart, pituitary gland, adrenal gland, placenta and regions of the brain. -
配列類似性
Belongs to the cytochrome P450 family. -
細胞内局在
Endoplasmic reticulum membrane. Microsome membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 539047 Cow
- Entrez Gene: 1592 Human
- Entrez Gene: 13082 Mouse
- Entrez Gene: 154985 Rat
- Omim: 602239 Human
- SwissProt: O43174 Human
- SwissProt: O55127 Mouse
- Unigene: 150595 Human
see all -
別名
- CP26 antibody
- CP26A_HUMAN antibody
- CYP26 antibody
see all
画像
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Anti-CYP26A1 antibody (ab151968) at 1/1000 dilution + 293T whole cell lysate at 30 µg
Predicted band size: 56 kDa
7.5% SDS PAGE -
Immunohistochemical analysis of paraffin-embedded Human hepatoma tissue labeling CYP26A1 with ab151968 at 1/500 dilution.
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Immunohistochemical analysis of paraffin-embedded Mouse muscle tissue labeling CYP26A1 with ab151968 at 1/500 dilution.
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (4)
ab151968 は 4 報の論文で使用されています。
- Li DD et al. Cytochrome P450 26A1 regulates the clusters and killing activity of NK cells during the peri-implantation period. J Cell Mol Med 26:2438-2450 (2022). PubMed: 35297206
- Wei DP et al. A novel Cytochrome P450 26A1 expressing NK cell subset at the mouse maternal-foetal interface. J Cell Mol Med 25:1771-1782 (2021). PubMed: 33438367
- Ji WH et al. Cytochrome P450 26A1 Modulates the Polarization of Uterine Macrophages During the Peri-Implantation Period. Front Immunol 12:763067 (2021). PubMed: 34712245
- Gu AQ et al. Cytochrome P450 26A1 modulates uterine dendritic cells in mice early pregnancy. J Cell Mol Med 23:5403-5414 (2019). PubMed: 31148354