Anti-CD3 抗体 [PS1] (ab699)
Key features and details
- Mouse monoclonal [PS1] to CD3
- Suitable for: IHC-Fr, IHC-P, ICC/IF, WB
- Reacts with: Human
- Isotype: IgG2a
製品の概要
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製品名
Anti-CD3 antibody [PS1]
CD3 一次抗体 製品一覧 -
製品の詳細
Mouse monoclonal [PS1] to CD3 -
由来種
Mouse -
特異性
This antibody, when used in conjunction with UCHL-1, is regarded as a reliable pan T-cell marker for immunophenotyping of lymphomas (See reference). Exceptions include some of the more aggressive, high-grade T cell lymphomas, which may not express detectable antigen. This antibody does not react with B-cells. -
アプリケーション
適用あり: IHC-Fr, IHC-P, ICC/IF, WBmore details -
種交差性
交差種: Human -
免疫原
Fusion protein corresponding to CD3. Prokaryotic fusion protein corresponding to the epsilon chain of CD3
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ポジティブ・コントロール
- Tonsil or T-cell lymphoma. IHC-P: Human colon tissue and colorectal mucosa tissue. IHC-Fr: Human skin tissue.
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特記事項
This antibody works well when used in combination with ab972 - Antigen retrieval solution - heat mediated high pH 9.5.The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
バッファー
Preservative: 0.09% Sodium azide
Constituents: 97.5% Water, 0.99% BSA, 0.33% Tris HCl, 0.04% Tween, 0.007% Hydrochloric acid -
Concentration information loading...
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精製度
Affinity purified -
ポリ/モノ
モノクローナル -
クローン名
PS1 -
ミエローマ
unknown -
アイソタイプ
IgG2a -
軽鎖の種類
unknown -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
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Related Products
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab699の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
---|---|---|
IHC-Fr | (1) |
Use at an assay dependent concentration.
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IHC-P | (3) |
Use at an assay dependent concentration.
|
ICC/IF | (3) |
Use at an assay dependent concentration.
|
WB | (4) |
Use at an assay dependent concentration. Predicted molecular weight: 19 kDa. PubMed: 21654633
|
特記事項 |
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IHC-Fr
Use at an assay dependent concentration. |
IHC-P
Use at an assay dependent concentration. |
ICC/IF
Use at an assay dependent concentration. |
WB
Use at an assay dependent concentration. Predicted molecular weight: 19 kDa. PubMed: 21654633 |
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (33)
ab699 は 33 報の論文で使用されています。
- Jiang H et al. Revealing the transcriptional heterogeneity of organ-specific metastasis in human gastric cancer using single-cell RNA Sequencing. Clin Transl Med 12:e730 (2022). PubMed: 35184420
- Xing X et al. Effect of neoadjuvant chemotherapy on the immune microenvironment in gastric cancer as determined by multiplex immunofluorescence and T cell receptor repertoire analysis. J Immunother Cancer 10:N/A (2022). PubMed: 35361730
- Hou Z et al. Prognostic significance and therapeutic potential of the immune checkpoint VISTA in pancreatic cancer. J Cancer Res Clin Oncol 147:517-531 (2021). PubMed: 33237432
- Zhang Q et al. Interrogation of the microenvironmental landscape in spinal ependymomas reveals dual functions of tumor-associated macrophages. Nat Commun 12:6867 (2021). PubMed: 34824203
- Derakhshan S et al. Evaluation of squamous cell carcinoma antigen 1 expression in oral squamous cell carcinoma (tumor cells and peritumoral T-lymphocytes) and verrucous carcinoma and comparison with normal oral mucosa. J Appl Oral Sci 29:e20210374 (2021). PubMed: 34878006