Anti-CCR6 抗体 (ab78429)
Key features and details
- Rabbit polyclonal to CCR6
- Suitable for: WB
- Reacts with: Rat, Human
- Isotype: IgG
リコンビナント抗体で、ロット間での高い再現性を実現
- 異なるロット間での安定した再現性
- 容易なスケールアップ
- 評価試験による特異性の確認済み
- 倫理基準に準拠 - アニマル・フリーの生産
製品の概要
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製品名
Anti-CCR6 antibody
CCR6 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to CCR6 -
由来種
Rabbit -
特異性
No cross reactivity with other proteins.
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アプリケーション
適用あり: WBmore details -
種交差性
交差種: Rat, Human
交差が予測される動物種: Mouse, Dog -
免疫原
Synthetic peptide corresponding to Human CCR6 aa 358-374 (C terminal). Different from the related rat and mouse sequences by two amino acids.
Sequence:RQTSETADNDNASSFTM
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ポジティブ・コントロール
- WB: Rat liver tissue lysate and SW620 and CEM cell lysates.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles. -
バッファー
Preservative: 0.025% Sodium azide
Constituents: 0.45% Sodium chloride, 0.1% Dibasic monohydrogen sodium phosphate, 2% Trehalose -
Concentration information loading...
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精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab78429の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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WB |
Use a concentration of 0.1 - 0.5 µg/ml. Predicted molecular weight: 42 kDa.
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特記事項 |
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WB
Use a concentration of 0.1 - 0.5 µg/ml. Predicted molecular weight: 42 kDa. |
ターゲット情報
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機能
Receptor for a C-C type chemokine. Binds to MIP-3-alpha/LARC and subsequently transduces a signal by increasing the intracellular calcium ions level. -
組織特異性
Spleen, lymph nodes, appendix, and fetal liver. Expressed in lymphocytes, T-cells and B-cells but not in natural killer cells, monocytes or granulocytes. -
配列類似性
Belongs to the G-protein coupled receptor 1 family. -
細胞内局在
Cell membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 1235 Human
- Entrez Gene: 12458 Mouse
- Entrez Gene: 308163 Rat
- Omim: 601835 Human
- SwissProt: P51684 Human
- SwissProt: O54689 Mouse
- Unigene: 46468 Human
- Unigene: 8007 Mouse
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別名
- BN 1 antibody
- BN1 antibody
- C C chemokine receptor type 6 antibody
see all
画像
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (15)
ab78429 は 15 報の論文で使用されています。
- Shigeoka M et al. Tongue Cancer Cell-Derived CCL20 Induced by Interaction With Macrophages Promotes CD163 Expression on Macrophages. Front Oncol 11:667174 (2021). PubMed: 34178651
- Bharucha JP et al. Human Beta-Defensin 2 and 3 Inhibit HIV-1 Replication in Macrophages. Front Cell Infect Microbiol 11:535352 (2021). PubMed: 34277460
- Ahn JH et al. Age-dependent alterations in the immunoreactivity of macrophage inflammatory protein-3a and its receptor CCR6 in the gerbil hippocampus. Mol Med Rep 22:1317-1324 (2020). PubMed: 32627009
- Wang T et al. Alleviation of Synovial Inflammation of Juanbi-Tang on Collagen-Induced Arthritis and TNF-Tg Mice Model. Front Pharmacol 11:45 (2020). PubMed: 32116720
- Chang KC et al. Stem cell characteristics promote aggressiveness of diffuse large B-cell lymphoma. Sci Rep 10:21342 (2020). PubMed: 33288848