Anti-Aspartate Aminotransferase 抗体 (ab85857)
Key features and details
- Goat polyclonal to Aspartate Aminotransferase
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-Aspartate Aminotransferase antibody
Aspartate Aminotransferase 一次抗体 製品一覧 -
製品の詳細
Goat polyclonal to Aspartate Aminotransferase -
由来種
Goat -
アプリケーション
適用あり: WB, IHC-Pmore details -
種交差性
交差種: Human
交差が予測される動物種: Rat, Pig, Chimpanzee, Cynomolgus monkey, Orangutan -
免疫原
Synthetic peptide:
RSYRYWDAEKR
by a Cysteine residue linker, corresponding to C terminal amino acids 157-167 of Human Aspartate Aminotransferase -
ポジティブ・コントロール
- Human kidney and heart tissue, Human Liver lysate.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
バッファー
pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: Tris buffered saline, 0.5% BSA -
Concentration information loading...
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精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab85857の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
---|---|---|
WB |
Use a concentration of 0.01 - 0.1 µg/ml. Predicted molecular weight: 46 kDa.
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IHC-P |
Use a concentration of 2.5 - 5 µg/ml.
|
特記事項 |
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WB
Use a concentration of 0.01 - 0.1 µg/ml. Predicted molecular weight: 46 kDa. |
IHC-P
Use a concentration of 2.5 - 5 µg/ml. |
ターゲット情報
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機能
Plays a key role in amino acid metabolism. -
配列類似性
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. -
細胞内局在
Cytoplasm. - Information by UniProt
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参照データベース
- Entrez Gene: 450664 Chimpanzee
- Entrez Gene: 101865666 Cynomolgus monkey
- Entrez Gene: 2805 Human
- Entrez Gene: 100173864 Orangutan
- Entrez Gene: 396967 Pig
- Entrez Gene: 24401 Rat
- Omim: 138180 Human
- SwissProt: A5A6K8 Chimpanzee
see all -
別名
- AATC_HUMAN antibody
- Aspartate aminotransferase 1 antibody
- Aspartate aminotransferase antibody
see all
画像
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ab85857 at 5 µg/ml staining Aspartate Aminotransferase in formalin fixed and paraffin embedded Human Kidney tissue.
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ab85857 at 5 µg/ml staining Aspartate Aminotransferase in formalin fixed and paraffin embedded Human heart tissue.
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Anti-Aspartate Aminotransferase antibody (ab85857) at 0.01 µg/ml + Human Liver lysate at 35 µg
Developed using the ECL technique.
Predicted band size: 46 kDa
Observed band size: 46 kDa
プロトコール
データシートおよび資料
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Datasheet download
参考文献 (3)
ab85857 は 3 報の論文で使用されています。
- Guo Y et al. Tumor Cell Derived Exosomal GOT1 Suppresses Tumor Cell Ferroptosis to Accelerate Pancreatic Cancer Progression by Activating Nrf2/HO-1 Axis via Upregulating CCR2 Expression. Cells 11:N/A (2022). PubMed: 36497150
- Untereiner AA et al. Drug resistance induces the upregulation of H2S-producing enzymes in HCT116 colon cancer cells. Biochem Pharmacol 149:174-185 (2018). WB . PubMed: 29061341
- Kästle M et al. Histone deacetylase 6 (HDAC6) plays a crucial role in p38MAPK-dependent induction of heme oxygenase-1 (HO-1) in response to proteasome inhibition. Free Radic Biol Med : (2012). PubMed: 23010497