Anti-Albumin 抗体 (ab106582)
Key features and details
- Chicken polyclonal to Albumin
- Suitable for: WB, IHC-P
- Reacts with: Mouse, Human
- Isotype: IgY
製品の概要
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製品名
Anti-Albumin antibody
Albumin 一次抗体 製品一覧 -
製品の詳細
Chicken polyclonal to Albumin -
由来種
Chicken -
アプリケーション
適用あり: WB, IHC-Pmore details -
種交差性
交差種: Mouse, Human -
免疫原
Synthetic peptide corresponding to Human Albumin (internal sequence). The immunogen is located within amino acids 340 - 390 of Albumin.
Database link: P02768 -
ポジティブ・コントロール
- Mouse liver lysate; Human liver tissue
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特記事項
Antibodies should not be exposed to prolonged high temperatures.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at +4°C. -
バッファー
pH: 7.2
Preservative: 0.02% Sodium azide
Constituent: PBS -
Concentration information loading...
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精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgY -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Positive Controls
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab106582の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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WB |
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 69 kDa.
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IHC-P | (7) |
Use a concentration of 2.5 - 20 µg/ml.
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IF |
Use a concentration of 20 µg/ml.
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特記事項 |
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WB
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 69 kDa. |
IHC-P
Use a concentration of 2.5 - 20 µg/ml. |
IF
Use a concentration of 20 µg/ml. |
ターゲット情報
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機能
Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc. -
組織特異性
Plasma. -
関連疾患
Defects in ALB are a cause of familial dysalbuminemic hyperthyroxinemia (FDH) [MIM:103600]. FDH is a form of euthyroid hyperthyroxinemia that is due to increased affinity of ALB for T(4). It is the most common cause of inherited euthyroid hyperthyroxinemia in Caucasian population. -
配列類似性
Belongs to the ALB/AFP/VDB family.
Contains 3 albumin domains. -
翻訳後修飾
Kenitra variant is partially O-glycosylated at Thr-620. It has two new disulfide bonds Cys-600 to Cys-602 and Cys-601 to Cys-606.
Glycated in diabetic patients.
Phosphorylation sites are present in the extracelllular medium.
Acetylated on Lys-223 by acetylsalicylic acid. -
細胞内局在
Secreted. - Information by UniProt
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参照データベース
- Entrez Gene: 213 Human
- Entrez Gene: 11657 Mouse
- Omim: 103600 Human
- SwissProt: P02768 Human
- SwissProt: P07724 Mouse
- Unigene: 418167 Human
- Unigene: 592379 Human
- Unigene: 16773 Mouse
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製品の状態
There are 2 isoforms produced by alternative splicing. -
別名
- alb antibody
- ALBU_HUMAN antibody
- Albumin (32 AA) antibody
see all
画像
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Lane 1 : Anti-Albumin antibody (ab106582) at 1 µg/ml
Lane 2 : Anti-Albumin antibody (ab106582) at 2 µg/ml
All lanes : Mouse liver tissue lysate
Lysates/proteins at 15 µg per lane.
Predicted band size: 69 kDa -
Immunohistochemical analysis of paraffin embedded Human liver tissue section labelling Albumin with ab106582 at 2.5 µg/ml.
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Immunohistochemical analysis of paraffin embedded Mouse liver tissue section labelling Albumin with ab106582 at 5 µg/ml.
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Immunofluorescence analysis of paraffin embedded mouse liver tissue section labelling Albumin with ab106582 at 20 µg/mL.
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (49)
ab106582 は 49 報の論文で使用されています。
- Luo W et al. MD2 deficiency prevents high-fat diet-induced AMPK suppression and lipid accumulation through regulating TBK1 in non-alcoholic fatty liver disease. Clin Transl Med 12:e777 (2022). PubMed: 35343085
- Dobric A et al. Cigarette Smoke Exposure Induces Neurocognitive Impairments and Neuropathological Changes in the Hippocampus. Front Mol Neurosci 15:893083 (2022). PubMed: 35656006
- Wang N et al. Identification of novel prognostic risk signature of breast cancer based on ferroptosis-related genes. Sci Rep 12:13766 (2022). PubMed: 35962042
- Miri-Lavasani Z et al. Conjugated Linoleic Acid Treatment Attenuates Cancerous features in Hepatocellular Carcinoma Cells. Stem Cells Int 2022:1850305 (2022). PubMed: 36132168
- Leng L et al. Serum proteome profiling provides a deep understanding of the 'gut-liver axis' in relation to liver injury and regeneration. Acta Biochim Biophys Sin (Shanghai) 53:372-380 (2021). PubMed: 33511977