2-Deoxy-D-glucose, glucose analog (ab142242)
Key features and details
- Non-metabolizable glucose analog and glycolytic inhibitor. Antitumor agent.
- CAS Number: 154-17-6
- Purity: > 97%
Soluble in Water >15 mg/mL or DMSO >15 mg/mL.
- Form / State: Solid
- Source: Synthetic
製品の概要
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製品名
2-Deoxy-D-glucose, glucose analog -
製品の詳細
Non-metabolizable glucose analog and glycolytic inhibitor. Antitumor agent. -
精製度
> 97% -
CAS 番号
154-17-6 -
構造式
製品の特性
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体系名
(4R,5S,6R)-6-(Hydroxymethyl)oxane-2,4,5-triol
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分子量
164.16 -
PubChem 登録番号
439268 -
保存方法
Store at Room Temperature. The product can be stored for up to 12 months. -
溶解性
Soluble in Water >15 mg/mL or DMSO >15 mg/mL.
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使用に関する注意
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES 線形表記
C1C(C(C(OC1O)CO)O)O -
由来
Synthetic
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研究分野
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
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Datasheet download
参考文献 (4)
ab142242 は 4 報の論文で使用されています。
- Wang Z et al. The Fibrillin-1/VEGFR2/STAT2 signaling axis promotes chemoresistance via modulating glycolysis and angiogenesis in ovarian cancer organoids and cells. Cancer Commun (Lond) 42:245-265 (2022). PubMed: 35234370
- Blancke Soares A et al. High-resolution spatiotemporal pHe and pO2 imaging in head and neck and oesophageal carcinoma cells. Cancer Metab 9:21 (2021). PubMed: 33947450
- Morein D et al. Continuous Inflammatory Stimulation Leads via Metabolic Plasticity to a Prometastatic Phenotype in Triple-Negative Breast Cancer Cells. Cells 10:N/A (2021). PubMed: 34072893
- Cabezas-Cruz A et al. Anaplasma phagocytophilum Infection Subverts Carbohydrate Metabolic Pathways in the Tick Vector, Ixodes scapularis. Front Cell Infect Microbiol 7:23 (2017). PubMed: 28229048