2-Chloro-N6-cyclopentyladenosine (CCPA), A1 agonist (ab120434)
Key features and details
- Highly potent, selective A1 agonist
- CAS Number: 37739-05-2
- Soluble in water to 5 mM and in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
製品の概要
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製品名
2-Chloro-N6-cyclopentyladenosine (CCPA), A1 agonist -
製品の詳細
Highly potent, selective A1 agonist -
別名
- CCPA
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生理活性の詳細
Highly potent and selective A1 receptor agonist (Ki values are 0.8, 2300 and 42 nM for human A1, A2A and A3 receptors, respectively). Shows >2000-fold selectivity over A2A. Centrally active following systemic administration and anticonvulsive in vivo.
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CAS 番号
37739-05-2 -
構造式
製品の特性
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体系名
2-Chloro-N-cyclopentyladenosine -
分子量
369.81 -
分子式
C15H20ClN5O4 -
PubChem 登録番号
123807 -
保存方法
Store at Room Temperature. Store under desiccating conditions. The product can be stored for up to 12 months. -
溶解性
Soluble in water to 5 mM and in DMSO to 100 mM -
使用に関する注意
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES 線形表記
Clc3nc(NC1CCCC1)c4ncn([C@@H]2O[C@H](CO)[C@H](O)C2O)c4n3 -
由来
Synthetic
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研究分野
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
参考文献 (2)
ab120434 は 2 報の論文で使用されています。
- Fujimoto K et al. Adenosine Attenuates Aortic Smooth Muscle Cell Calcification through A3 Adenosine Receptor. Tohoku J Exp Med 249:275-283 (2019). PubMed: 31875581
- Yi X et al. Adenosine receptors enhance the ATP-induced odontoblastic differentiation of human dental pulp cells. Biochem Biophys Res Commun 497:850-856 (2018). PubMed: 29454963