Anti-15-LOX-2 抗体 (ab23691)
Key features and details
- Rabbit polyclonal to 15-LOX-2
- Suitable for: WB
- Reacts with: Human, Pig
- Isotype: IgG
製品の概要
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製品名
Anti-15-LOX-2 antibody
15-LOX-2 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to 15-LOX-2 -
由来種
Rabbit -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Human, Pig
非交差種: Rabbit -
免疫原
Synthetic peptide corresponding to Human 15-LOX-2 aa 163-181.
Sequence:CLDEKTVEDLELNIKYSTA
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ポジティブ・コントロール
- Human prostate homogenate.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
バッファー
pH: 7.40
Preservative: 0.02% Sodium azide
Constituents: Tris buffered saline, 50% Glycerol, 0.1% BSA -
Concentration information loading...
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精製度
Immunogen affinity purified -
特記事項(精製)
This antibody was affinity purified. -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab23691の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
---|---|---|
WB |
Use a concentration of 3 µg/ml. Predicted molecular weight: 76 kDa.
Or 1/200. |
特記事項 |
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WB
Use a concentration of 3 µg/ml. Predicted molecular weight: 76 kDa. Or 1/200. |
ターゲット情報
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機能
Converts arachidonic acid exclusively to 15S-hydroperoxyeicosatetraenoic acid, while linoleic acid is less well metabolized. -
組織特異性
Expressed in hair, prostate, lung and cornea. -
パスウェイ
Lipid metabolism; leukotriene D4 biosynthesis. -
配列類似性
Belongs to the lipoxygenase family.
Contains 1 lipoxygenase domain.
Contains 1 PLAT domain. -
細胞内局在
Cytoplasm. - Information by UniProt
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参照データベース
- Entrez Gene: 247 Human
- Omim: 603697 Human
- SwissProt: O15296 Human
- Unigene: 111256 Human
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別名
- 15 Lipoxygenase 2 antibody
- 15 LO 2 antibody
- 15 LOX 2 antibody
see all
画像
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (14)
ab23691 は 14 報の論文で使用されています。
- Dar HH et al. P. aeruginosa augments irradiation injury via 15-lipoxygenase-catalyzed generation of 15-HpETE-PE and induction of theft-ferroptosis. JCI Insight 7:N/A (2022). PubMed: 35041620
- Miek L et al. Staphylococcus aureus controls eicosanoid and specialized pro-resolving mediator production via lipoteichoic acid. Immunology 166:47-67 (2022). PubMed: 35143048
- Zhang K et al. Modulation of Inflammation-Related Lipid Mediator Pathways by Celastrol During Human Macrophage Polarization. J Inflamm Res 15:3285-3304 (2022). PubMed: 35676971
- Van Anh TT et al. From Vietnamese plants to a biflavonoid that relieves inflammation by triggering the lipid mediator class switch to resolution. Acta Pharm Sin B 11:1629-1647 (2021). PubMed: 34221873
- Zhao D et al. Enteral nutrition ameliorates the symptoms of Crohn's disease in mice via activating special pro-resolving mediators through innate lymphoid cells. Innate Immun 27:533-542 (2021). PubMed: 34791916