Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Constituents: 2% Sucrose, PBS
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Immunogen affinity purified
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
||Use a concentration of 1 µg/ml. Predicted molecular weight: 34 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.
Acts as an E2-dependent E3 ubiquitin-protein ligase. May be involved in endocytic trafficking.
Expressed at extremely low levels in normal breast, prostate, lung, colon. Higher levels of expression are detected in heart, skeletal muscle, testis as well as in breast and prostate cancer cells.
Protein modification; protein ubiquitination.
Contains 1 RING-type zinc finger.
RING-type zinc finger-dependent and E2-dependent autoubiquitination.
Cytoplasm > cytosol. The GTP-bound form of RAB7A recruits RNF115 from the cytosol onto late endosomes/lysosomes.
Information by UniProt
- BCA2 antibody
- Breast cancer associated gene 2 antibody
- CL469780 antibody
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